RTF1 and TCEA1

Data Source:
BioGRID (pull down)

		RTF1	TCEA1
Description		RTF1 homolog, Paf1/RNA polymerase II complex component	transcription elongation factor A1
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GO Annotations	Cellular Component	Nucleoplasm Nucleolus Cdc73/Paf1 Complex	Nucleoplasm Transcription Factor TFIID Complex Nucleolus
	Molecular Function	Single-stranded DNA Binding RNA Binding Protein Binding RNA Polymerase II C-terminal Domain Phosphoserine Binding	DNA Binding Protein Binding Zinc Ion Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Endodermal Cell Fate Commitment Blastocyst Growth Transcription By RNA Polymerase II Transcription Elongation From RNA Polymerase II Promoter Wnt Signaling Pathway Protein Ubiquitination Stem Cell Population Maintenance Positive Regulation Of Histone H3-K4 Methylation Histone H3-K4 Trimethylation	Transcription-coupled Nucleotide-excision Repair Transcription By RNA Polymerase II Transcription Elongation From RNA Polymerase II Promoter Positive Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Exoribonuclease Activity
Pathways		Formation of RNA Pol II elongation complex RNA Polymerase II Pre-transcription Events RNA Polymerase II Transcription Elongation E3 ubiquitin ligases ubiquitinate target proteins	Formation of RNA Pol II elongation complex Formation of HIV elongation complex in the absence of HIV Tat Formation of HIV-1 elongation complex containing HIV-1 Tat Pausing and recovery of Tat-mediated HIV elongation Tat-mediated HIV elongation arrest and recovery Tat-mediated elongation of the HIV-1 transcript HIV elongation arrest and recovery Pausing and recovery of HIV elongation RNA Polymerase II Pre-transcription Events Formation of TC-NER Pre-Incision Complex Transcription-Coupled Nucleotide Excision Repair (TC-NER) Dual incision in TC-NER Gap-filling DNA repair synthesis and ligation in TC-NER TP53 Regulates Transcription of DNA Repair Genes RNA Polymerase II Transcription Elongation
Drugs
Diseases
GWAS		Allergic disease (asthma, hay fever or eczema) ( 29083406 29785011) Allergic rhinitis ( 30013184) Asthma ( 32296059) Coronary artery disease ( 29212778) Eosinophil percentage of granulocytes ( 27863252) Height ( 20881960) Itch intensity from mosquito bite ( 28199695) Ulcerative colitis ( 28067908)	Urinary albumin-to-creatinine ratio ( 26631737)
Interacting Genes		3 interacting genes: APP SRPK2 TCEA1	18 interacting genes: APP CDC73 CDK7 CIR1 CTDP1 CTR9 EAF2 GPKOW GTF2E1 GTF2F2 IWS1 LEO1 PAF1 POLR2A REXO1 RTF1 UBR5 WDR61
Entrez ID		23168	6917
HPRD ID		11071	03252
Ensembl ID		ENSG00000137815	ENSG00000187735
Uniprot IDs		Q92541	A0A384MTX4 B7Z4W0 P23193
PDB IDs		2BZE 2DB9 3U1U 4L1P 4L1U 6TED	1TFI 3NDQ 5IY6 5IY7 5IY8 5IYA 5IYB 5IYC 6O9L
Enriched GO Terms of Interacting Partners?
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