MAPKBP1 and KEAP1

  • Data Source:
  • BioGRID (two hybrid)

MAPKBP1

KEAP1

Description mitogen-activated protein kinase binding protein 1 kelch like ECH associated protein 1
Image No pdb structure
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Diastolic blood pressure ( 27841878)
  • Urinary albumin excretion ( 30220432)
  • Waist-to-hip ratio adjusted for BMI (additive genetic model) ( 30778226)
  • Body mass index and waist-hip ratio (pleiotropy) ( 29868124)
  • Chronic inflammatory diseases (ankylosing spondylitis, Crohn's disease, psoriasis, primary sclerosing cholangitis, ulcerative colitis) (pleiotropy) ( 26974007)
  • Crohn's disease ( 28067908)
  • Inflammatory bowel disease ( 28067908)
Interacting Genes 62 interacting genes: ADAM12 ADAMTSL4 ALG13 APTX CTDSP1 CYSRT1 FOXN1 GLRX3 HOXA1 KEAP1 KPRP KRT31 KRT34 KRT35 KRT38 KRT40 KRT86 KRTAP1-1 KRTAP1-3 KRTAP10-1 KRTAP10-3 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP12-3 KRTAP13-1 KRTAP26-1 KRTAP3-1 KRTAP3-2 KRTAP4-12 KRTAP5-6 KRTAP5-7 KRTAP5-9 KRTAP6-3 KRTAP9-2 KRTAP9-3 KRTAP9-4 MAPK10 MAPK8 MAPK9 MDFI MEOX2 METTL15 MYOG NBPF19 NOTCH2NLA PLA2G10 PLSCR3 RBCK1 RGS20 SIAH1 SPRY2 SPRY3 TCF12 TCF4 TEKT5 TEX11 TRIM27 TRIM42 TRIP6 YPEL5 ZNF34 77 interacting genes: AK4 AMER1 ANKS1A ATG5 BAD BPTF C2orf68 CARD10 CAT CCNB1IP1 CDH1 CDK6 CLU COL1A1 COL2A1 CPEB2 CSNK2A1 CTTN CUL3 DPP3 EAF1 EGFR ERICH5 ETF1 FAM117B GLRX5 GPR151 GYPA HSP90AA1 HSP90AB1 ICAM1 IFIH1 IPO11 IQCC IRF1 KLHL2 KLHL3 KPNA6 LAMTOR5 LSM3 MAD2L1 MAPKBP1 MCM3 MCMBP MYO7A NFE2L2 NIBAN2 NTAQ1 NUDT4 NUP50 OXR1 PALB2 PAQR4 PDCD6IP PPP1R13L PRKAG1 PTMA RAF1 RECK RELA SMARCD1 SNRPN SQSTM1 STAP2 STK3 STK4 TBC1D7 TENT5A TERF1 TET2 TRIM15 UBC USP15 WDR83 WHRN ZNF121 ZSCAN32
Entrez ID 23005 9817
HPRD ID 17465 12079
Ensembl ID ENSG00000137802 ENSG00000079999
Uniprot IDs O60336 A0A024R7C0 Q14145
PDB IDs 1U6D 1ZGK 2FLU 3VNG 3VNH 3ZGC 3ZGD 4CXI 4CXJ 4CXT 4IFJ 4IFL 4IFN 4IN4 4IQK 4L7B 4L7C 4L7D 4N1B 4XMB 5DAD 5DAF 5F72 5GIT 5NLB 5WFL 5WFV 5WG1 5WHL 5WHO 5WIY 5X54 6FFM 6FMP 6FMQ 6HWS 6LRZ 6ROG 6SP1 6SP4 6T7V 6T7Z 6TG8 6TYM 6TYP 6UF0 6V6Z 6W66 6W67 6W68 6W69 6WCQ
Enriched GO Terms of Interacting Partners?
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