RALY and PLOD3

Data Source:
BioGRID (two hybrid)

		RALY	PLOD3
Description		RALY heterogeneous nuclear ribonucleoprotein	procollagen-lysine,2-oxoglutarate 5-dioxygenase 3
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GO Annotations	Cellular Component	Nucleus Catalytic Step 2 Spliceosome	Extracellular Space Endoplasmic Reticulum Endoplasmic Reticulum Lumen Endoplasmic Reticulum Membrane Rough Endoplasmic Reticulum Golgi Apparatus Trans-Golgi Network Collagen-containing Extracellular Matrix Extracellular Exosome
	Molecular Function	Transcription Coregulator Activity RNA Binding Protein Binding	Iron Ion Binding Protein Binding Procollagen-lysine 5-dioxygenase Activity L-ascorbic Acid Binding Procollagen Glucosyltransferase Activity Procollagen Galactosyltransferase Activity
	Biological Process	MRNA Splicing, Via Spliceosome Regulation Of Transcription, DNA-templated Cholesterol Homeostasis Regulation Of Nucleic Acid-templated Transcription	In Utero Embryonic Development Endothelial Cell Morphogenesis Protein O-linked Glycosylation Protein Localization Peptidyl-lysine Hydroxylation Protein Phosphopantetheinylation Neural Tube Development Collagen Fibril Organization Cellular Response To Hormone Stimulus Collagen Metabolic Process Vasodilation Hydroxylysine Biosynthetic Process Epidermis Morphogenesis Lung Morphogenesis Basement Membrane Assembly
Pathways			Collagen biosynthesis and modifying enzymes
Drugs			Ascorbic acid
Diseases
GWAS		Adult body size ( 32376654) Basal cell carcinoma ( 31174203 27539887) Blond vs. brown/black hair color ( 30531825) Breast cancer ( 22976474) Cancer ( 27197191) Cancer (pleiotropy) ( 27197191) Cutaneous malignant melanoma ( 32341527) Cutaneous squamous cell carcinoma ( 32041948) Estimated glomerular filtration rate ( 31451708) Facial pigmentation ( 25705849) Hair color ( 29662168) HDL cholesterol levels ( 32203549) Idiopathic dilated cardiomyopathy ( 29495422) Keratinocyte cancer (MTAG) ( 31174203) Low tan response ( 29739929) Melanoma ( 28212542) Nevus count or cutaneous melanoma ( 32341527) Non-melanoma skin cancer ( 29739929) Red cell distribution width ( 32888494) Red vs. brown/black hair color ( 30531825) Refractive error ( 32231278) Skin colour saturation ( 25963972) Skin sensitivity to sun ( 25963972) Spherical equivalent or myopia (age of diagnosis) ( 29808027) Squamous cell carcinoma ( 26829030) Type 2 diabetes ( 30297969) Vitiligo ( 27723757) Weight ( 28552196) Youthful appearance (self-reported) ( 32339537)	Blood protein levels ( 30072576)
Interacting Genes		31 interacting genes: BCCIP BYSL CELF1 EXOC7 GTPBP3 HNRNPC HNRNPCL1 HNRNPD HNRNPH1 HNRNPK HSF2BP KHDRBS1 LNX1 MRPL38 MTUS2 PCBP1 PIK3CD PLOD3 QKI RALYL RBPMS2 RPL9 SDCBP SKA2 SPG7 THAP1 TIGD3 WDR62 ZBTB24 ZNF408 ZNF76	20 interacting genes: CCDC85B COIL COL17A1 CRIP3 DPPA2 EFHC2 EHMT2 FAM153A IP6K2 KCTD9 KHNYN L3MBTL3 LINC00839 NAB2 RAB3IP RALY RHOU RHOXF2 SORBS3 ZNF620
Entrez ID		22913	8985
HPRD ID		11480	04347
Ensembl ID		ENSG00000125970	ENSG00000106397
Uniprot IDs		Q53GL6 Q9UKM9	O60568 Q9UG85
PDB IDs		1WF1	6FXK 6FXM 6FXR 6FXT 6FXX 6FXY
Enriched GO Terms of Interacting Partners?
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