PLOD3 and CCDC85B

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		PLOD3	CCDC85B
Description		procollagen-lysine,2-oxoglutarate 5-dioxygenase 3	coiled-coil domain containing 85B
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Space Endoplasmic Reticulum Endoplasmic Reticulum Lumen Endoplasmic Reticulum Membrane Rough Endoplasmic Reticulum Golgi Apparatus Trans-Golgi Network Collagen-containing Extracellular Matrix Extracellular Exosome	Nucleus Cytoplasm Centrosome Adherens Junction
	Molecular Function	Iron Ion Binding Protein Binding Procollagen-lysine 5-dioxygenase Activity L-ascorbic Acid Binding Procollagen Glucosyltransferase Activity Procollagen Galactosyltransferase Activity	Protein Binding Delta-catenin Binding
	Biological Process	In Utero Embryonic Development Endothelial Cell Morphogenesis Protein O-linked Glycosylation Protein Localization Peptidyl-lysine Hydroxylation Protein Phosphopantetheinylation Neural Tube Development Collagen Fibril Organization Cellular Response To Hormone Stimulus Collagen Metabolic Process Vasodilation Hydroxylysine Biosynthetic Process Epidermis Morphogenesis Lung Morphogenesis Basement Membrane Assembly	Viral Process Cell Differentiation Negative Regulation Of Cell Growth Negative Regulation Of Fat Cell Differentiation Negative Regulation Of Transcription, DNA-templated
Pathways		Collagen biosynthesis and modifying enzymes
Drugs		Ascorbic acid
Diseases
GWAS		Blood protein levels ( 30072576)	Acne (severe) ( 24927181) Asthma ( 31959851)
Interacting Genes		20 interacting genes: CCDC85B COIL COL17A1 CRIP3 DPPA2 EFHC2 EHMT2 FAM153A IP6K2 KCTD9 KHNYN L3MBTL3 LINC00839 NAB2 RAB3IP RALY RHOU RHOXF2 SORBS3 ZNF620	138 interacting genes: AGGF1 AKAP17A AKIRIN2 APEX2 AQP1 BEX2 BEX3 BIRC5 C19orf25 C21orf91 C2CD6 C7orf50 C8orf48 CARD9 CCDC112 CCDC116 CCDC120 CCDC185 CCDC33 CCNK CDK18 CDKN1A CENPP CEP70 CFAP53 CHCHD3 COPS4 CWC25 DEPP1 DEUP1 DOK5 DTNB DUSP13 EIF3H ENKD1 EPS8 EXOC7 EXOC8 EZH2 FAM107A FAM124B FAM13C FAM214B FAM27E3 FAM50B FAM74A4 FASTKD5 FBF1 FCHSD2 FNDC11 FXR2 GCC1 GFI1B GPANK1 HMG20B HNRNPC IKZF5 INO80B KANSL1 KIAA0408 KRT17 KRT18 KRT20 KRT6A LDOC1 LMO3 LNX1 LZTS2 MBIP MCM10 MCRS1 MEAF6 MOAP1 MOB1A MOB4 NDUFA5 NEK6 NIF3L1 NRIP1 NUP54 ODAD4 PBXIP1 PIDD1 PKN1 PLEKHF2 PLOD3 POLR2L PRC1 PRPF3 PSMA1 PSMC1 PSMC6 PSMF1 RALYL RBM41 RBM7 RGS8 RIBC2 RNF8 SCNM1 SETD5 SF3A3 SIX1 SLU7 SMARCD1 SPATA46 SYT17 SYTL4 TASOR2 TCEANC TCHP TEAD4 THAP7 TNNI1 TNNT1 TSPYL4 TTC14 TUBGCP4 USP2 UTP14A UTP6 VPS72 ZBTB16 ZBTB5 ZC2HC1C ZFC3H1 ZFP36 ZNF165 ZNF205 ZNF250 ZNF337 ZNF417 ZNF426 ZNF564 ZNF587 ZNF638 ZNF764 ZNF821
Entrez ID		8985	11007
HPRD ID		04347	16101
Ensembl ID		ENSG00000106397	ENSG00000175602
Uniprot IDs		O60568 Q9UG85	Q15834
PDB IDs		6FXK 6FXM 6FXR 6FXT 6FXX 6FXY
Enriched GO Terms of Interacting Partners?
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