RALY and QKI

Data Source:
BioGRID (two hybrid, two hybrid)

		RALY	QKI
Description		RALY heterogeneous nuclear ribonucleoprotein	QKI, KH domain containing RNA binding
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GO Annotations	Cellular Component	Nucleus Catalytic Step 2 Spliceosome	Nucleus Cytoplasm Synapse
	Molecular Function	Transcription Coregulator Activity RNA Binding Protein Binding	RNA Binding MRNA Binding Protein Binding SH3 Domain Binding
	Biological Process	MRNA Splicing, Via Spliceosome Regulation Of Transcription, DNA-templated Cholesterol Homeostasis Regulation Of Nucleic Acid-templated Transcription	Vasculogenesis MRNA Processing Regulation Of Translation Spermatid Development RNA Splicing Positive Regulation Of Gene Expression Myelination Muscle Cell Differentiation Long-chain Fatty Acid Biosynthetic Process Regulation Of MRNA Splicing, Via Spliceosome MRNA Transport
Pathways			Signaling by BRAF and RAF fusions
Drugs
Diseases
GWAS		Adult body size ( 32376654) Basal cell carcinoma ( 31174203 27539887) Blond vs. brown/black hair color ( 30531825) Breast cancer ( 22976474) Cancer ( 27197191) Cancer (pleiotropy) ( 27197191) Cutaneous malignant melanoma ( 32341527) Cutaneous squamous cell carcinoma ( 32041948) Estimated glomerular filtration rate ( 31451708) Facial pigmentation ( 25705849) Hair color ( 29662168) HDL cholesterol levels ( 32203549) Idiopathic dilated cardiomyopathy ( 29495422) Keratinocyte cancer (MTAG) ( 31174203) Low tan response ( 29739929) Melanoma ( 28212542) Nevus count or cutaneous melanoma ( 32341527) Non-melanoma skin cancer ( 29739929) Red cell distribution width ( 32888494) Red vs. brown/black hair color ( 30531825) Refractive error ( 32231278) Skin colour saturation ( 25963972) Skin sensitivity to sun ( 25963972) Spherical equivalent or myopia (age of diagnosis) ( 29808027) Squamous cell carcinoma ( 26829030) Type 2 diabetes ( 30297969) Vitiligo ( 27723757) Weight ( 28552196) Youthful appearance (self-reported) ( 32339537)	Diastolic blood pressure ( 27841878) Diisocyanate-induced asthma ( 25918132) Height ( 31562340) Hemoglobin ( 32888494) Incident myocardial infarction ( 26950853) Mean corpuscular hemoglobin ( 29403010) Mean corpuscular volume ( 29403010) Mosaic loss of chromosome Y (Y chromosome dosage) ( 28346444) Platelet distribution width ( 32888494) Red blood cell count ( 29403010) Refractive error ( 32231278) Response to TNF antagonist treatment ( 18615156) Seasonality and depression ( 30217971) Triglyceride levels ( 32203549) Type 2 diabetes ( 30297969 30718926)
Interacting Genes		31 interacting genes: BCCIP BYSL CELF1 EXOC7 GTPBP3 HNRNPC HNRNPCL1 HNRNPD HNRNPH1 HNRNPK HSF2BP KHDRBS1 LNX1 MRPL38 MTUS2 PCBP1 PIK3CD PLOD3 QKI RALYL RBPMS2 RPL9 SDCBP SKA2 SPG7 THAP1 TIGD3 WDR62 ZBTB24 ZNF408 ZNF76	50 interacting genes: APP ATXN1 CARM1 CCND3 CDKN2D DAZ1 DAZ4 DEPP1 DMRTB1 FBXO7 FHL3 FUBP3 HCLS1 HNRNPH2 HNRNPK IL7R LSM3 MIR141 MIR19B2 MIR200A MIR34B MIR34C MIR7-1 NABP1 PCBP1 PCBP2 PCBP4 PIAS1 PRKAB2 PRMT1 PSMF1 PTBP1 PTBP2 RALY RBFOX1 RBFOX2 RBM11 RBM14 RBM23 RBPMS RNF138 SERF2 SNRPA TEX11 THAP1 TIAL1 TSG101 U2AF2 USH1C WDR77
Entrez ID		22913	9444
HPRD ID		11480	06691
Ensembl ID		ENSG00000125970	ENSG00000112531
Uniprot IDs		Q53GL6 Q9UKM9	Q8WY44 Q96PU8
PDB IDs		1WF1	4JVH
Enriched GO Terms of Interacting Partners?
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