DOLK and KCNA3

Data Source:
BioGRID (two hybrid)

		DOLK	KCNA3
Description		dolichol kinase	potassium voltage-gated channel subfamily A member 3
Image		No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Membrane Integral Component Of Endoplasmic Reticulum Membrane	Plasma Membrane Voltage-gated Potassium Channel Complex Integral Component Of Membrane Axon Calyx Of Held Membrane Raft Glutamatergic Synapse Integral Component Of Postsynaptic Membrane Integral Component Of Presynaptic Membrane
	Molecular Function	Dolichol Kinase Activity Protein Binding	Voltage-gated Ion Channel Activity Voltage-gated Potassium Channel Activity Delayed Rectifier Potassium Channel Activity Protein Binding Outward Rectifier Potassium Channel Activity
	Biological Process	Dolichyl Diphosphate Biosynthetic Process Phosphorylation Dolichyl Monophosphate Biosynthetic Process	Potassium Ion Transport Regulation Of Ion Transmembrane Transport Protein Homooligomerization Potassium Ion Transmembrane Transport
Pathways		Synthesis of Dolichyl-phosphate Defective DOLK causes DOLK-CDG (CDG-1m)	Voltage gated Potassium channels
Drugs			Enflurane Clofazimine Promethazine Miconazole Dalfampridine
Diseases		Congenital disorders of glycosylation (CDG) type I
GWAS			Acute lymphoblastic leukemia (childhood) ( 22076464)
Interacting Genes		22 interacting genes: APPBP2 CD79A CHODL CREB3 CREB3L1 EDA FAM209A FNDC9 GALNT8 GJA8 GPX8 KCNA1 KCNA10 KCNA3 KCNA6 LRRC4C SLC7A6 SYNPR TMEM45B TMEM80 UBQLN1 VSIR	10 interacting genes: BAX CAV1 CD3D DEFB4A DLG1 DLG4 DOLK IL16 KCNA1 KCNA2
Entrez ID		22845	3738
HPRD ID		15525	15937
Ensembl ID		ENSG00000175283	ENSG00000177272
Uniprot IDs		A0A0S2Z597 Q9UPQ8	P22001
PDB IDs			4BGC
Enriched GO Terms of Interacting Partners?
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