KCNA3 and IL16

Data Source:
HPRD (two hybrid)

		KCNA3	IL16
Description		potassium voltage-gated channel subfamily A member 3	interleukin 16
Image
GO Annotations	Cellular Component	Plasma Membrane Voltage-gated Potassium Channel Complex Integral Component Of Membrane Axon Calyx Of Held Membrane Raft Glutamatergic Synapse Integral Component Of Postsynaptic Membrane Integral Component Of Presynaptic Membrane	Extracellular Region Extracellular Space Cytosol Plasma Membrane Focal Adhesion Nuclear Speck Flemming Body
	Molecular Function	Voltage-gated Ion Channel Activity Voltage-gated Potassium Channel Activity Delayed Rectifier Potassium Channel Activity Protein Binding Outward Rectifier Potassium Channel Activity	Cytokine Activity CD4 Receptor Binding
	Biological Process	Potassium Ion Transport Regulation Of Ion Transmembrane Transport Protein Homooligomerization Potassium Ion Transmembrane Transport	Immune Response Viral Process Cytokine-mediated Signaling Pathway Leukocyte Chemotaxis Positive Regulation Of Interleukin-1 Alpha Production Positive Regulation Of Interleukin-12 Production Positive Regulation Of Interleukin-6 Production Positive Regulation Of Inflammatory Response Induction Of Positive Chemotaxis Regulation Of Calcium Ion Transport
Pathways		Voltage gated Potassium channels	Other interleukin signaling
Drugs		Enflurane Clofazimine Promethazine Miconazole Dalfampridine
Diseases
GWAS		Acute lymphoblastic leukemia (childhood) ( 22076464)	Blood protein levels ( 30072576 29875488 28240269) Blood protein levels in cardiovascular risk ( 28369058) Body mass index ( 26426971) Brown vs. black hair color ( 30531825) Colorectal cancer (aspirin and/or NSAID use interaction) ( 25781442) Height ( 31562340) Inattentive symptoms ( 18821565) Interleukin-16 levels ( 27989323) Lymphocyte counts ( 32888494) Monocyte count ( 32888494) Primary biliary cholangitis ( 28425483)
Interacting Genes		10 interacting genes: BAX CAV1 CD3D DEFB4A DLG1 DLG4 DOLK IL16 KCNA1 KCNA2	108 interacting genes: ANXA6 BLZF1 BOLA2 BOLA2B CALCOCO2 CAMK1 CARD10 CASP3 CCDC184 CCDC33 CD4 CDK1 CEP72 CSNK2A1 CSNK2A2 CYSRT1 DMRTB1 DUSP7 EFEMP2 FAM124A FHL2 FHL5 FTO GABPB1 GOLGA2 GOLGA6L9 GRIN2A GRIN2B GRIN2C GRIN2D HDAC3 HOMEZ HOOK2 HSF2BP JAKMIP1 KANK2 KCNA3 KCND1 KCND2 KCNJ10 KCNJ15 KCNJ2 KCNJ4 KCTD9 KDM1A KIF16B KIFC3 KRT31 KRT86 KRTAP1-1 KRTAP1-3 KRTAP10-8 KRTAP3-1 L3MBTL3 LGALS14 LMO3 LNX1 LNX2 MBD3L1 MID2 MIER2 MTUS2 MYOG NOXA1 NTAQ1 OIP5 PDLIM7 PFDN5 PICK1 PPP1R12A PPP1R12B PPP1R12C PPP1R16A PRDM6 PRR13 PSTPIP1 RAPGEF2 RBCK1 RNF144B SERTAD3 SMARCB1 SOHLH1 SPRED1 SUV39H1 TEPSIN TFIP11 TRIB3 TRIM23 TRIM27 TRIM42 TRIP6 UBXN11 USHBP1 WWTR1 ZBTB39 ZIM2 ZNF143 ZNF165 ZNF474 ZNF526 ZNF572 ZNF581 ZNF620 ZNF774 ZNF777 ZNF835 ZNRD2 ZRANB1
Entrez ID		3738	3603
HPRD ID		15937	04329
Ensembl ID		ENSG00000177272	ENSG00000172349
Uniprot IDs		P22001	Q14005 Q9UME6
PDB IDs		4BGC	1I16 1X6D 5FB8
Enriched GO Terms of Interacting Partners?
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