DOLK and SLC7A6

Data Source:
BioGRID (two hybrid)

		DOLK	SLC7A6
Description		dolichol kinase	solute carrier family 7 member 6
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Membrane Integral Component Of Endoplasmic Reticulum Membrane	Plasma Membrane Integral Component Of Plasma Membrane Basolateral Plasma Membrane Intracellular Membrane-bounded Organelle
	Molecular Function	Dolichol Kinase Activity Protein Binding	Protein Binding Amino Acid Transmembrane Transporter Activity Basic Amino Acid Transmembrane Transporter Activity L-amino Acid Transmembrane Transporter Activity Antiporter Activity
	Biological Process	Dolichyl Diphosphate Biosynthetic Process Phosphorylation Dolichyl Monophosphate Biosynthetic Process	Amino Acid Transmembrane Transport Amino Acid Transport L-amino Acid Transport Ornithine Transport Leukocyte Migration L-alpha-amino Acid Transmembrane Transport Basic Amino Acid Transmembrane Transport
Pathways		Synthesis of Dolichyl-phosphate Defective DOLK causes DOLK-CDG (CDG-1m)	Basigin interactions Amino acid transport across the plasma membrane
Drugs
Diseases		Congenital disorders of glycosylation (CDG) type I
GWAS			Blood metabolite levels ( 24816252) Blood metabolite ratios ( 24816252) Body mass index ( 28552196) Estimated glomerular filtration rate ( 31152163 30604766) Glomerular filtration rate (creatinine) ( 28452372 26831199) Metabolic traits ( 21886157) Refractive error ( 32231278) Schizophrenia ( 25056061 29483656 30285260) Serum metabolite levels ( 23093944)
Interacting Genes		22 interacting genes: APPBP2 CD79A CHODL CREB3 CREB3L1 EDA FAM209A FNDC9 GALNT8 GJA8 GPX8 KCNA1 KCNA10 KCNA3 KCNA6 LRRC4C SLC7A6 SYNPR TMEM45B TMEM80 UBQLN1 VSIR	1 interacting genes: DOLK
Entrez ID		22845	9057
HPRD ID		15525	12031
Ensembl ID		ENSG00000175283	ENSG00000103064
Uniprot IDs		A0A0S2Z597 Q9UPQ8	A0A024R719 Q92536
PDB IDs
Enriched GO Terms of Interacting Partners?
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