DLGAP4 and SLC9A3R2

Data Source:
BioGRID (two hybrid)

		DLGAP4	SLC9A3R2
Description		DLG associated protein 4	SLC9A3 regulator 2
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Neuromuscular Junction Glutamatergic Synapse Cholinergic Synapse Postsynaptic Specialization	Nucleus Plasma Membrane Focal Adhesion Endomembrane System Apical Plasma Membrane Extracellular Exosome
	Molecular Function	Protein Binding Molecular Adaptor Activity	Signaling Receptor Binding Protein Binding Beta-catenin Binding Protein C-terminus Binding Phosphatase Binding Type 2 Metabotropic Glutamate Receptor Binding Type 3 Metabotropic Glutamate Receptor Binding Identical Protein Binding Protein-membrane Adaptor Activity Cadherin Binding
	Biological Process	Signaling Regulation Of Postsynaptic Neurotransmitter Receptor Activity	Protein-containing Complex Assembly Protein Localization To Plasma Membrane
Pathways		Neurexins and neuroligins Neurexins and neuroligins
Drugs
Diseases
GWAS		Low density lipoprotein cholesterol levels ( 32154731) Neuroblastoma or malignant cutaneous melanoma ( 31605138)	Diastolic blood pressure ( 27841878 30578418) Hematocrit ( 32888494) Hemoglobin ( 32888494) Hemoglobin levels ( 32327693) High light scatter reticulocyte count ( 32888494) Platelet distribution width ( 32888494) Pulse pressure ( 30578418) Red blood cell count ( 32888494) Reticulocyte count ( 32888494) Systolic blood pressure ( 27841878 30578418)
Interacting Genes		32 interacting genes: ABI2 ALDH16A1 ATPAF2 BIN1 DLG1 DLG3 DLG4 EXOC4 FHL3 FHL5 FKBP6 FYN GRIN1 GRIN2D MAGEA6 MPP7 MTUS2 NCK1 NCK2 PALS1 PLP2 PPP1R1B SH3GL2 SH3RF1 SHANK2 SHANK3 SLC9A3R1 SLC9A3R2 SORBS2 SYNGAP1 UBASH3A UBC	41 interacting genes: ABCC4 ACTN4 ADORA2B ADRB2 ATP2B2 CFTR DLGAP4 EZR KCNJ1 LPAR1 LPAR2 P2RY1 PDGFRB PDPK1 PDZK1 PLCB3 PODXL PRKACA PRKCA PTEN PTH1R RDX RPS6KA1 SGK1 SGK3 SIAH1 SLC13A1 SLC22A4 SLC22A5 SLC22A9 SLC26A3 SLC34A1 SLC9A3 SLCO1A2 SLCO3A1 SRY TAZ TBC1D10A TRAF4 WWP2 WWTR1
Entrez ID		22839	9351
HPRD ID		16826	05946
Ensembl ID		ENSG00000080845	ENSG00000065054
Uniprot IDs		A0A0B4J2C2 Q9Y2H0	Q15599
PDB IDs			2D11 2HE4 2OCS 4P0C
Enriched GO Terms of Interacting Partners?
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