SLC9A3R2 and KCNJ1

Data Source:
BioGRID (pull down, two hybrid)
HPRD (in vivo, in vitro, two hybrid)

		SLC9A3R2	KCNJ1
Description		SLC9A3 regulator 2	potassium inwardly rectifying channel subfamily J member 1
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Plasma Membrane Focal Adhesion Endomembrane System Apical Plasma Membrane Extracellular Exosome	Plasma Membrane Voltage-gated Potassium Channel Complex
	Molecular Function	Signaling Receptor Binding Protein Binding Beta-catenin Binding Protein C-terminus Binding Phosphatase Binding Type 2 Metabotropic Glutamate Receptor Binding Type 3 Metabotropic Glutamate Receptor Binding Identical Protein Binding Protein-membrane Adaptor Activity Cadherin Binding	Inward Rectifier Potassium Channel Activity ATP Binding Phosphatidylinositol-4,5-bisphosphate Binding ATP-activated Inward Rectifier Potassium Channel Activity
	Biological Process	Protein-containing Complex Assembly Protein Localization To Plasma Membrane	Potassium Ion Transport Excretion Regulation Of Ion Transmembrane Transport Potassium Ion Import Across Plasma Membrane
Pathways			Potassium transport channels
Drugs			Bethanidine Glimepiride Minoxidil Acetohexamide Tolbutamide Glymidine Yohimbine Agmatine Butamben
Diseases			Bartter syndrome
GWAS		Diastolic blood pressure ( 27841878 30578418) Hematocrit ( 32888494) Hemoglobin ( 32888494) Hemoglobin levels ( 32327693) High light scatter reticulocyte count ( 32888494) Platelet distribution width ( 32888494) Pulse pressure ( 30578418) Red blood cell count ( 32888494) Reticulocyte count ( 32888494) Systolic blood pressure ( 27841878 30578418)
Interacting Genes		41 interacting genes: ABCC4 ACTN4 ADORA2B ADRB2 ATP2B2 CFTR DLGAP4 EZR KCNJ1 LPAR1 LPAR2 P2RY1 PDGFRB PDPK1 PDZK1 PLCB3 PODXL PRKACA PRKCA PTEN PTH1R RDX RPS6KA1 SGK1 SGK3 SIAH1 SLC13A1 SLC22A4 SLC22A5 SLC22A9 SLC26A3 SLC34A1 SLC9A3 SLCO1A2 SLCO3A1 SRY TAZ TBC1D10A TRAF4 WWP2 WWTR1	6 interacting genes: GOLGA3 PRKCD SGK1 SH3RF1 SLC9A3R1 SLC9A3R2
Entrez ID		9351	3758
HPRD ID		05946	08981
Ensembl ID		ENSG00000065054	ENSG00000151704
Uniprot IDs		Q15599	A0A024R3K6 A8K432 P48048
PDB IDs		2D11 2HE4 2OCS 4P0C
Enriched GO Terms of Interacting Partners?
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