TSPO2 and BIK

Data Source:
BioGRID (two hybrid)

		TSPO2	BIK
Description		translocator protein 2	BCL2 interacting killer
Image		No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Plasma Membrane Integral Component Of Membrane Organelle Membrane	Endomembrane System Integral Component Of Membrane Mitochondrial Membrane
	Molecular Function	Protein Binding Cholesterol Binding	Protein Binding
	Biological Process	Intracellular Cholesterol Transport Lipid Droplet Organization Enucleate Erythrocyte Differentiation Amino Acid Import Across Plasma Membrane Import Across Plasma Membrane	Apoptotic Process Male Gonad Development Apoptotic Mitochondrial Changes Positive Regulation Of Protein-containing Complex Assembly Regulation Of Apoptotic Process Positive Regulation Of Release Of Cytochrome C From Mitochondria
Pathways
Drugs
Diseases
GWAS		Gastric cancer ( 26129866) Non-cardia gastric cancer ( 26129866)	Prostate cancer ( 25939597 21743057) Prostate cancer (SNP x SNP interaction) ( 22219177)
Interacting Genes		58 interacting genes: AHNAK2 AQP6 ARL13B ASGR2 ASZ1 BIK CD53 CD69 CD79A CERS4 CLDN4 CNR2 COL4A5 CPLX4 CREB3L1 DKK4 EBP EFNA5 EMP1 ERGIC3 ERP29 FCER1G FCGR1A FFAR2 FNDC9 FXYD3 GGT7 GJB5 GPR152 GPR42 IGFBP5 KCNJ6 KLRC1 LRRC59 MAL MARCHF2 MFF MFSD6 MS4A1 PDZK1IP1 PLEKHO1 PSCA RELL2 RETREG3 RPRM SLC10A1 SLC10A6 SLC16A2 SLC34A2 SLC41A3 SLC7A1 SPAG4 STOM SYT2 TMEM140 TMEM54 TMEM80 VSIR	95 interacting genes: ADGRE2 ADIPOQ AIG1 ALG8 ANKRD46 APOD APP ASB11 BCL2 BCL2A1 BCL2L1 BCL2L10 BCL2L2 BMP10 BNIP3 BRICD5 BTN2A2 C14orf180 C3orf52 C4orf3 CD53 CD72 CLDN19 CMTM5 CMTM7 CNIH1 CNIH3 CREB3 CRKL CTXN3 CXCL16 CYB561 CYB5B ELOVL4 ERGIC3 EXOC3L2 FAM209A FAM241B FAM3C FATE1 FCGR1A GPX8 GRM2 INSIG2 KCNN4 MARCHF5 MCL1 MS4A13 NAT8 NR2F2 NRM PBX3 PGAP2 PGRMC1 PLN PLP1 PLP2 PLPP4 REEP4 RUSF1 S100A1 SCAMP4 SEC22A SELENOK SERP1 SERP2 SLC35E3 SLC37A4 SLC39A7 SMIM1 SOCS3 STRIT1 STX8 TANK TMBIM1 TMEM107 TMEM11 TMEM14B TMEM14C TMEM199 TMEM222 TMEM229B TMEM243 TMEM254 TMEM60 TMEM80 TMEM86B TMEM97 TRARG1 TSPO2 UBE2D1 UBIAD1 VAMP3 VAMP5 ZFPL1
Entrez ID		222642	638
HPRD ID		16569	04547
Ensembl ID		ENSG00000112212	ENSG00000100290
Uniprot IDs		Q5TGU0	A0A024R4X6 Q13323
PDB IDs			2IPE
Enriched GO Terms of Interacting Partners?
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