TSPO2 and DKK4

Data Source:
BioGRID (two hybrid)

		TSPO2	DKK4
Description		translocator protein 2	dickkopf WNT signaling pathway inhibitor 4
Image		No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Plasma Membrane Integral Component Of Membrane Organelle Membrane	Cellular_component Extracellular Space
	Molecular Function	Protein Binding Cholesterol Binding	Molecular_function Protein Binding Co-receptor Binding Receptor Antagonist Activity
	Biological Process	Intracellular Cholesterol Transport Lipid Droplet Organization Enucleate Erythrocyte Differentiation Amino Acid Import Across Plasma Membrane Import Across Plasma Membrane	Multicellular Organism Development Wnt Signaling Pathway Negative Regulation Of Wnt Signaling Pathway Negative Regulation Of Hair Follicle Placode Formation Negative Regulation Of Canonical Wnt Signaling Pathway Negative Regulation Of Signaling Receptor Activity
Pathways			TCF dependent signaling in response to WNT Negative regulation of TCF-dependent signaling by WNT ligand antagonists Signaling by LRP5 mutants
Drugs
Diseases
GWAS		Gastric cancer ( 26129866) Non-cardia gastric cancer ( 26129866)
Interacting Genes		58 interacting genes: AHNAK2 AQP6 ARL13B ASGR2 ASZ1 BIK CD53 CD69 CD79A CERS4 CLDN4 CNR2 COL4A5 CPLX4 CREB3L1 DKK4 EBP EFNA5 EMP1 ERGIC3 ERP29 FCER1G FCGR1A FFAR2 FNDC9 FXYD3 GGT7 GJB5 GPR152 GPR42 IGFBP5 KCNJ6 KLRC1 LRRC59 MAL MARCHF2 MFF MFSD6 MS4A1 PDZK1IP1 PLEKHO1 PSCA RELL2 RETREG3 RPRM SLC10A1 SLC10A6 SLC16A2 SLC34A2 SLC41A3 SLC7A1 SPAG4 STOM SYT2 TMEM140 TMEM54 TMEM80 VSIR	3 interacting genes: GIMAP5 ITGAM TSPO2
Entrez ID		222642	27121
HPRD ID		16569	05660
Ensembl ID		ENSG00000112212	ENSG00000104371
Uniprot IDs		Q5TGU0	Q9UBT3
PDB IDs			5O57
Enriched GO Terms of Interacting Partners?
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