TIGD3 and RALY

Data Source:
BioGRID (two hybrid)

		TIGD3	RALY
Description		tigger transposable element derived 3	RALY heterogeneous nuclear ribonucleoprotein
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus	Nucleus Catalytic Step 2 Spliceosome
	Molecular Function	DNA Binding Protein Binding	Transcription Coregulator Activity RNA Binding Protein Binding
	Biological Process		MRNA Splicing, Via Spliceosome Regulation Of Transcription, DNA-templated Cholesterol Homeostasis Regulation Of Nucleic Acid-templated Transcription
Pathways
Drugs
Diseases
GWAS		Acne (severe) ( 24927181)	Adult body size ( 32376654) Basal cell carcinoma ( 31174203 27539887) Blond vs. brown/black hair color ( 30531825) Breast cancer ( 22976474) Cancer ( 27197191) Cancer (pleiotropy) ( 27197191) Cutaneous malignant melanoma ( 32341527) Cutaneous squamous cell carcinoma ( 32041948) Estimated glomerular filtration rate ( 31451708) Facial pigmentation ( 25705849) Hair color ( 29662168) HDL cholesterol levels ( 32203549) Idiopathic dilated cardiomyopathy ( 29495422) Keratinocyte cancer (MTAG) ( 31174203) Low tan response ( 29739929) Melanoma ( 28212542) Nevus count or cutaneous melanoma ( 32341527) Non-melanoma skin cancer ( 29739929) Red cell distribution width ( 32888494) Red vs. brown/black hair color ( 30531825) Refractive error ( 32231278) Skin colour saturation ( 25963972) Skin sensitivity to sun ( 25963972) Spherical equivalent or myopia (age of diagnosis) ( 29808027) Squamous cell carcinoma ( 26829030) Type 2 diabetes ( 30297969) Vitiligo ( 27723757) Weight ( 28552196) Youthful appearance (self-reported) ( 32339537)
Interacting Genes		5 interacting genes: PNMA3 RALY RALYL TLE5 UBE2I	31 interacting genes: BCCIP BYSL CELF1 EXOC7 GTPBP3 HNRNPC HNRNPCL1 HNRNPD HNRNPH1 HNRNPK HSF2BP KHDRBS1 LNX1 MRPL38 MTUS2 PCBP1 PIK3CD PLOD3 QKI RALYL RBPMS2 RPL9 SDCBP SKA2 SPG7 THAP1 TIGD3 WDR62 ZBTB24 ZNF408 ZNF76
Entrez ID		220359	22913
HPRD ID		18187	11480
Ensembl ID		ENSG00000173825	ENSG00000125970
Uniprot IDs		Q6B0B8	Q53GL6 Q9UKM9
PDB IDs			1WF1
Enriched GO Terms of Interacting Partners?
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