FANCD2 and FANCE

Data Source:
HPRD (two hybrid)

		FANCD2	FANCE
Description		FA complementation group D2	FA complementation group E
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GO Annotations	Cellular Component	Condensed Chromosome Nucleus Nucleoplasm Nucleolus Cytosol Nuclear Body	Nucleus Nucleoplasm Fanconi Anaemia Nuclear Complex
	Molecular Function	Protein Binding DNA Polymerase Binding	Molecular_function
	Biological Process	Homologous Chromosome Pairing At Meiosis Gamete Generation Response To Gamma Radiation Intra-S DNA Damage Checkpoint Cellular Response To Oxidative Stress Interstrand Cross-link Repair Regulation Of Regulatory T Cell Differentiation Brain Morphogenesis Regulation Of Inflammatory Response Regulation Of DNA-binding Transcription Factor Activity Neuronal Stem Cell Population Maintenance Double-strand Break Repair Involved In Meiotic Recombination Regulation Of CD40 Signaling Pathway	Interstrand Cross-link Repair
Pathways		Fanconi Anemia Pathway TP53 Regulates Transcription of DNA Repair Genes	Fanconi Anemia Pathway
Drugs
Diseases		Fanconi anemia	Fanconi anemia
GWAS		Alzheimer's disease ( 24755620) Waist-to-hip ratio adjusted for BMI ( 28552196)	Height ( 28552196) Ovarian cancer ( 30557369) Pulmonary function (smoking interaction) ( 23284291)
Interacting Genes		28 interacting genes: ATM ATR BLM BRCA1 BRCA2 BRIP1 FANCC FANCE FANCI FANCL H2AC4 H2BC3 H3C1 H4C1 MEN1 MRE11 NBN PCNA RAD51 TERF1 TNFRSF1A TNFRSF1B TNKS UBB UBE2T UHRF1 UHRF2 USP1	8 interacting genes: BRCA2 CHEK1 FANCA FANCC FANCD2 FANCF FANCG HES1
Entrez ID		2177	2178
HPRD ID		01968	02943
Ensembl ID		ENSG00000144554	ENSG00000112039
Uniprot IDs		Q9BXW9	Q9HB96
PDB IDs		6VAA 6VAD 6VAE 6VAF	2ILR
Enriched GO Terms of Interacting Partners?
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