ETV1 and KCNA2

Data Source:
HPRD (in vivo)

		ETV1	KCNA2
Description		ETS variant transcription factor 1	potassium voltage-gated channel subfamily A member 2
Image			No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus	Endoplasmic Reticulum Membrane Plasma Membrane Integral Component Of Plasma Membrane Voltage-gated Potassium Channel Complex Integral Component Of Membrane Lamellipodium Axon Dendrite Lamellipodium Membrane Neuronal Cell Body Membrane Paranodal Junction Presynaptic Membrane Perikaryon Axon Terminus Juxtaparanode Region Of Axon
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Protein Binding Sequence-specific Double-stranded DNA Binding	Voltage-gated Potassium Channel Activity Delayed Rectifier Potassium Channel Activity Potassium Channel Activity Protein Binding
	Biological Process	Regulation Of Transcription By RNA Polymerase II Transcription By RNA Polymerase II Cell Differentiation Positive Regulation Of Transcription By RNA Polymerase II Peripheral Nervous System Neuron Development	Potassium Ion Transport Regulation Of Dopamine Secretion Neuronal Action Potential Sensory Perception Of Pain Regulation Of Ion Transmembrane Transport Protein Homooligomerization Potassium Ion Transmembrane Transport
Pathways			Voltage gated Potassium channels
Drugs			Enflurane Promethazine Miconazole Dalfampridine
Diseases		Ewing's sarcoma Prostate cancer
GWAS		Blond vs. brown/black hair color ( 30531825) Chronotype ( 30696823) Coronary artery disease ( 29212778) Coronary atherosclerosis (time to event) ( 32589924) Height ( 28552196 31217584) Intraocular pressure ( 30591961) Lymphocyte counts ( 32888494 27863252) Monocyte count ( 32888494) Platelet count ( 32888494) Plateletcrit ( 32888494) Post bronchodilator FEV1/FVC ratio in smoking ( 30068317) Post bronchodilator percent predicted FEV1 in smoking ( 30068317) Renal underexcretion gout ( 32238385) Type 2 diabetes ( 24509480 32499647 30718926) Verbal declarative memory ( 25648963) White blood cell count ( 32888494)	Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098)
Interacting Genes		19 interacting genes: ATR CCND3 EP300 ERG JUN KAT2B KCNA2 MAPK14 MAPK3 MAPK8 MAPKAPK2 NCOA2 NCOA3 NSMCE2 PRKACA RPS6KA1 RPS6KA5 SPI1 UBE2I	16 interacting genes: CAMLG CNTNAP2 CTTN DLG1 DLG4 ETV1 FAM3C KCNA3 KCNA4 KCNA5 KCNAB1 KCNAB2 NEU1 PTK2B PTPRA RHOA
Entrez ID		2115	3737
HPRD ID		02765	01443
Ensembl ID		ENSG00000006468	ENSG00000177301
Uniprot IDs		B5MCT2 B7Z2C9 P50549	P16389
PDB IDs		4AVP 4BNC 5ILS
Enriched GO Terms of Interacting Partners?
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