KCNA2 and KCNAB2

Data Source:
HPRD (in vivo)

		KCNA2	KCNAB2
Description		potassium voltage-gated channel subfamily A member 2	potassium voltage-gated channel subfamily A regulatory beta subunit 2
Image		No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Membrane Plasma Membrane Integral Component Of Plasma Membrane Voltage-gated Potassium Channel Complex Integral Component Of Membrane Lamellipodium Axon Dendrite Lamellipodium Membrane Neuronal Cell Body Membrane Paranodal Junction Presynaptic Membrane Perikaryon Axon Terminus Juxtaparanode Region Of Axon	Cytosol Microtubule Plasma Membrane Voltage-gated Potassium Channel Complex Membrane Extrinsic Component Of Cytoplasmic Side Of Plasma Membrane Specific Granule Membrane Juxtaparanode Region Of Axon Synapse Tertiary Granule Membrane Pinceau Fiber
	Molecular Function	Voltage-gated Potassium Channel Activity Delayed Rectifier Potassium Channel Activity Potassium Channel Activity Protein Binding	Aldo-keto Reductase (NADP) Activity Voltage-gated Potassium Channel Activity Protein Binding Potassium Channel Regulator Activity Ion Channel Binding
	Biological Process	Potassium Ion Transport Regulation Of Dopamine Secretion Neuronal Action Potential Sensory Perception Of Pain Regulation Of Ion Transmembrane Transport Protein Homooligomerization Potassium Ion Transmembrane Transport	Neutrophil Degranulation NADPH Oxidation Potassium Ion Transmembrane Transport Regulation Of Action Potential Regulation Of Potassium Ion Transmembrane Transport Regulation Of Protein Localization To Cell Surface
Pathways		Voltage gated Potassium channels	Voltage gated Potassium channels Neutrophil degranulation
Drugs		Enflurane Promethazine Miconazole Dalfampridine	Enflurane Promethazine Miconazole
Diseases
GWAS		Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098)	Metabolite levels ( 23823483)
Interacting Genes		16 interacting genes: CAMLG CNTNAP2 CTTN DLG1 DLG4 ETV1 FAM3C KCNA3 KCNA4 KCNA5 KCNAB1 KCNAB2 NEU1 PTK2B PTPRA RHOA	8 interacting genes: ATXN1 CD4 KCNA2 NEDD4 NEDD4L SLC39A1 SLC39A2 SQSTM1
Entrez ID		3737	8514
HPRD ID		01443	03090
Ensembl ID		ENSG00000177301	ENSG00000069424
Uniprot IDs		P16389	A1PR14 B2R776 Q13303
PDB IDs			1ZSX
Enriched GO Terms of Interacting Partners?
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