FAAP20 and PFDN5

Data Source:
BioGRID (two hybrid)

		FAAP20	PFDN5
Description		FA core complex associated protein 20	prefoldin subunit 5
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GO Annotations	Cellular Component	Nucleoplasm Chromosome Nuclear Body Cell Junction Fanconi Anaemia Nuclear Complex	Nucleus Cytoplasm Cytosol Prefoldin Complex Intermediate Filament Cytoskeleton
	Molecular Function	Protein Binding Polyubiquitin Modification-dependent Protein Binding Ubiquitin Binding Metal Ion Binding K63-linked Polyubiquitin Modification-dependent Protein Binding Ubiquitin-dependent Protein Binding	Amyloid-beta Binding Transcription Corepressor Activity Protein Binding Unfolded Protein Binding
	Biological Process	Cellular Response To DNA Damage Stimulus Translesion Synthesis Interstrand Cross-link Repair	Regulation Of Transcription, DNA-templated Protein Folding Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Canonical Wnt Signaling Pathway Negative Regulation Of Amyloid Fibril Formation
Pathways		Fanconi Anemia Pathway	Prefoldin mediated transfer of substrate to CCT/TriC
Drugs
Diseases
GWAS		Sedentary behaviour duration ( 30531941) TPE interval (resting) ( 32386560)
Interacting Genes		28 interacting genes: ARNT2 BPIFA1 CRX CT55 CTDSP1 DDIT4L DUSP21 FANCF GOLGA6L9 INCA1 KRTAP6-2 KRTAP8-1 LCN2 LMO2 LRP2BP MEOX2 MOB2 NFKBID PFDN5 PIN1 PRDM5 REL REV1 SERTAD1 SERTAD3 TEX11 TRIB3 UBC	114 interacting genes: ABI2 ANKRD55 BCAS2 BCL6 BHLHE40 BRMS1 C10orf55 C10orf62 C20orf85 C22orf39 C4orf45 C7orf31 CALCOCO2 CCDC198 CSPP1 DMRT3 DOK4 DOK5 ELK3 ESPNL FAAP20 FAM102A FAM110A FAM214B FAM221A FAM222B FAM90A1 GLRX3 GLYCTK GPANK1 GSTO2 GUCD1 HAPLN2 HHEX HOXB9 HOXC8 IKBKG IKZF3 IL16 INCA1 IRX2 IRX6 ITSN1 KCTD9 KDM1A KLHL38 KLHL42 LARP4 LNX1 MAP2K5 METTL21A MISP MRPL45 MYC MYOT MYOZ1 NEUROG2 NOXA1 NTAQ1 PATZ1 PAX9 PFDN2 PFDN6 PHF1 PHF24 PILRA PITX1 PITX2 POGZ PPP1R32 PRKAB2 PRPF18 PRR35 PSMB4 PSMB8 PSME3 RIBC1 RIPPLY1 RSRC2 RUSC1 SAXO1 SCNM1 SDCBP SHISA6 SLAIN1 SMAP1 SMG9 SNAI1 SNRNP25 SNRPB SOHLH1 SPAG8 SPG21 STK19 SYCE1L SYT17 TAF6L TBX3 TCF19 TFG TLE5 TP73 TRAPPC6A TRIM28 TUBA1B TUBA3C VAX2 VBP1 VEZF1 VGLL1 WDR25 YPEL5 ZC2HC1C ZNF148
Entrez ID		199990	5204
HPRD ID		08707	05359
Ensembl ID		ENSG00000162585	ENSG00000123349
Uniprot IDs		A0A024R0B3 Q6NZ36 Q6ZRT9 Q7Z4P6	Q99471
PDB IDs		2MUQ 2MUR 3WWQ	6NR8 6NR9 6NRB 6NRC 6NRD
Enriched GO Terms of Interacting Partners?
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