EIF2B1 and MED29

Data Source:
BioGRID (two hybrid)

		EIF2B1	MED29
Description		eukaryotic translation initiation factor 2B subunit alpha	mediator complex subunit 29
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol Eukaryotic Translation Initiation Factor 2B Complex Plasma Membrane Membrane	Nucleoplasm Mediator Complex
	Molecular Function	Translation Initiation Factor Activity Guanyl-nucleotide Exchange Factor Activity Protein Binding Identical Protein Binding	Transcription Coregulator Activity Protein Binding Transcription Factor Binding
	Biological Process	Translational Initiation Regulation Of Translational Initiation Response To Heat Response To Glucose Oligodendrocyte Development Response To Peptide Hormone Regulation Of Catalytic Activity T Cell Receptor Signaling Pathway	Regulation Of Transcription By RNA Polymerase II
Pathways		Recycling of eIF2:GDP	PPARA activates gene expression Transcriptional regulation of white adipocyte differentiation Transcriptional regulation of white adipocyte differentiation
Drugs
Diseases		Leukoencephalopathy with vanishing white matter; Vanishing white matter disease; Childhood ataxia with diffuse central nervous system hypomyelination (CACH); Cree leukoencephalopathy (CLE)
GWAS		Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		21 interacting genes: ADRA2A ADRA2B ADRA2C ADRB2 ARL4D ATF5 BZW2 C1orf50 CREBBP EIF2B2 EIF2S1 EIF2S2 EPM2A GORASP2 MED29 MRPL4 NTAQ1 RD3 TRIM59 TRIML2 UBE2I	13 interacting genes: ABI2 ABI3 BCAS2 EIF2B1 MED12 MED13 MED14 MED20 MED21 MED9 NRDE2 SSC5D USP47
Entrez ID		1967	55588
HPRD ID		09458	13748
Ensembl ID		ENSG00000111361	ENSG00000063322
Uniprot IDs		Q14232	B4DUA7 Q9NX70
PDB IDs		3ECS 6CAJ 6EZO 6K71 6K72 6O81 6O85 6O9Z
Enriched GO Terms of Interacting Partners?
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