CRMP1 and DPYSL2

Data Source:
BioGRID (two hybrid, two hybrid, two hybrid)
HPRD (in vivo)

		CRMP1	DPYSL2
Description		collapsin response mediator protein 1	dihydropyrimidinase like 2
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GO Annotations	Cellular Component	Nucleus Centrosome Spindle Cytosol Growth Cone Midbody Perikaryon	Cytosol Microtubule Plasma Membrane Membrane Extracellular Exosome
	Molecular Function	Dihydropyrimidinase Activity Protein Binding Filamin Binding Identical Protein Binding	Dihydropyrimidinase Activity Protein Binding Microtubule Binding Identical Protein Binding
	Biological Process	Microtubule Cytoskeleton Organization Nucleobase-containing Compound Metabolic Process Pyrimidine Nucleobase Catabolic Process Nervous System Development Axon Guidance Negative Regulation Of Neuron Projection Development Negative Regulation Of Actin Filament Binding	Nucleobase-containing Compound Metabolic Process Pyrimidine Nucleobase Catabolic Process Endocytosis Cytoskeleton Organization Signal Transduction Nervous System Development Axon Guidance Brain Development Regulation Of Axon Extension Regulation Of Neuron Differentiation
Pathways		CRMPs in Sema3A signaling	CRMPs in Sema3A signaling Recycling pathway of L1
Drugs			Artenimol
Diseases
GWAS		Blood trace element (Zn levels) ( 23720494) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Metabolite levels ( 23823483) Subcortical volume (MOSTest) ( 32665545)	Bitter alcoholic beverage consumption ( 31046077) Brain morphology (MOSTest) ( 32665545) Diastolic blood pressure ( 30224653) Diastolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858) Diastolic blood pressure x smoking status (ever vs never) interaction (2df test) ( 29455858) Systolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858)
Interacting Genes		80 interacting genes: AGR2 ALDH2 AMFR ANXA7 AP3M1 ARL15 AXIN1 BID BTBD2 CACNA1A CCDC106 CCL18 CCT7 CDK5RAP2 CDK5RAP3 DDX18 DNAJB11 DPYSL2 DPYSL3 DUSP4 EEF1D EIF2S2 EPN1 EXOSC8 FAS FTH1 FUBP1 FXR1 GNE GOLGA2 HDHD2 HGS HMGB1 HNRNPH1 HNRNPH3 HNRNPUL1 HSPE1 HTT IL33 KLHL20 LRRC1 LRRK2 LSM2 MAP3K20 MAPK8IP2 MCM3AP MOB4 MRPS12 NAT9 NDUFV2 NVL PAFAH1B3 PFN1 PLA2G2A PMF1 PPP1R8 PSMD11 RACK1 RGL2 RGS2 ROCK1 RPA2 RPS6KA5 RTN4 SAT1 SEPHS1 SERPINB9 SNRPG SPRY2 SRC TFG TK1 TRIP13 TSC22D1 UBE2A UBE2B VCP VIM YAE1 ZNF24	16 interacting genes: AP2A1 CDC42 CRMP1 DISC1 DPYSL3 DPYSL4 DPYSL5 GORASP2 GSK3B LEF1 NUMB PLD2 ROCK1 TNIK TUBB UBE2I
Entrez ID		1400	1808
HPRD ID		03913	03914
Ensembl ID		ENSG00000072832	ENSG00000092964
Uniprot IDs		B3KT07 B3KV96 E9PD68 Q14194 Q96I11 X5DNI1	A0A1C7CYX9 Q16555 Q59GB4
PDB IDs		4B3Z	2GSE 2VM8 5LXX 5MKV 5MLE 5X1A 5X1C 5X1D 5YZ5 5YZA 5YZB 6JV9 6JVB
Enriched GO Terms of Interacting Partners?
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