DNMT1 and BAZ2A

Data Source:
BioGRID (pull down)

		DNMT1	BAZ2A
Description		DNA methyltransferase 1	bromodomain adjacent to zinc finger domain 2A
Image
GO Annotations	Cellular Component	Nucleus Nucleoplasm	Chromatin Silencing Complex Nucleolus Cytosol Nuclear Speck RDNA Heterochromatin
	Molecular Function	DNA Binding DNA (cytosine-5-)-methyltransferase Activity Protein Binding Zinc Ion Binding DNA-methyltransferase Activity Promoter-specific Chromatin Binding	RNA Polymerase I Core Promoter Sequence-specific DNA Binding RNA Binding Protein Binding Nuclear Receptor Binding Histone Binding Metal Ion Binding Lysine-acetylated Histone Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II DNA Methylation Chromatin Organization Ras Protein Signal Transduction Maintenance Of DNA Methylation Positive Regulation Of Gene Expression Negative Regulation Of Gene Expression Negative Regulation Of Gene Expression, Epigenetic Positive Regulation Of Histone H3-K4 Methylation Negative Regulation Of Histone H3-K9 Methylation C-5 Methylation Of Cytosine Positive Regulation Of DNA Methylation-dependent Heterochromatin Assembly Positive Regulation Of Vascular Associated Smooth Muscle Cell Proliferation Negative Regulation Of Vascular Associated Smooth Muscle Cell Apoptotic Process Negative Regulation Of Vascular Associated Smooth Muscle Cell Differentiation Involved In Phenotypic Switching	RDNA Heterochromatin Assembly RNA Polymerase I Preinitiation Complex Assembly DNA Methylation Chromatin Remodeling Transcription, DNA-templated Regulation Of Transcription, DNA-templated Histone Deacetylation
Pathways		PRC2 methylates histones and DNA NoRC negatively regulates rRNA expression SUMOylation of DNA methylation proteins DNA methylation	NoRC negatively regulates rRNA expression
Drugs		Procaine Azacitidine Procainamide Flucytosine Decitabine Palifosfamide Epigallocatechin gallate
Diseases
GWAS		Birth weight ( 31043758) Immature fraction of reticulocytes ( 27863252) Narcolepsy ( 24204295) Offspring birth weight ( 31043758) Reticulocyte count ( 27863252) Reticulocyte fraction of red cells ( 27863252)	Mean platelet volume ( 22139419 32888494 27863252) Platelet count ( 22139419 32888494) Platelet distribution width ( 32888494)
Interacting Genes		41 interacting genes: AKT1 BAZ2A BRAP CBX1 CSNK2B DAXX DCAF5 DMAP1 DNMT3A DNMT3B DYNLL1 E2F6 EED EZH2 GSK3B H3-4 H3C1 HDAC1 HDAC2 HELLS HMGB1 L3MBTL3 LASP1 MECP2 NRIP1 PCLAF PCNA PRKAA2 RB1 RGS6 RPS6KA6 RUNX1 RUNX1T1 SETD7 SUMO2 SUV39H1 TRIM27 TSG101 UBB UHRF1 YWHAQ	8 interacting genes: ADRB2 DNMT1 DNMT3B H4C1 HDAC1 KAT8 SMARCA5 TTF1
Entrez ID		1786	11176
HPRD ID		00532	10417
Ensembl ID		ENSG00000130816	ENSG00000076108
Uniprot IDs		I6L9H2 P26358 Q59FP7	F8VU39 Q9UIF9
PDB IDs		3EPZ 3PTA 3SWR 4WXX 4YOC 4Z96 4Z97 5WVO 5YDR 6K3A	4LZ2 4Q6F 4QBM 4QF2 5AGQ 5MGJ 5MGK 5MGL 5MGM 5OR8 5T8R 6FAP 6FG6 6FGF 6FGG 6FGH 6FGI 6FGL 6FGV 6FGW 6FHU 6FI0 6FKP
Enriched GO Terms of Interacting Partners?
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