DHPS and RPL9

Data Source:
BioGRID (affinity chromatography technology, two hybrid)
HPRD (two hybrid)

		DHPS	RPL9
Description		deoxyhypusine synthase	ribosomal protein L9
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GO Annotations	Cellular Component	Cytoplasm Cytosol	Nucleus Cytosol Ribosome Focal Adhesion Membrane Cytosolic Large Ribosomal Subunit
	Molecular Function	Protein Binding Deoxyhypusine Synthase Activity Identical Protein Binding	RNA Binding Structural Constituent Of Ribosome Protein Binding RRNA Binding
	Biological Process	Translation Spermidine Metabolic Process Positive Regulation Of Cell Population Proliferation Peptidyl-lysine Modification To Peptidyl-hypusine	Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Cytoplasmic Translation Translation Translational Initiation SRP-dependent Cotranslational Protein Targeting To Membrane Viral Transcription
Pathways		Hypusine synthesis from eIF5A-lysine	L13a-mediated translational silencing of Ceruloplasmin expression Peptide chain elongation SRP-dependent cotranslational protein targeting to membrane SRP-dependent cotranslational protein targeting to membrane Viral mRNA Translation Selenocysteine synthesis Major pathway of rRNA processing in the nucleolus and cytosol Formation of a pool of free 40S subunits GTP hydrolysis and joining of the 60S ribosomal subunit Eukaryotic Translation Termination Regulation of expression of SLITs and ROBOs Response of EIF2AK4 (GCN2) to amino acid deficiency Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)
Drugs		1-Guanidinium-7-Aminoheptane
Diseases
GWAS		Platelet distribution width ( 32888494)	Alcohol consumption (drinks per week) ( 30643258)
Interacting Genes		16 interacting genes: BRCA1 EIF5A EIF5A2 LNX1 MEOX2 NIF3L1 NTAQ1 NUDT18 PAX6 PTPRH RAB27B RBP1 REL RPL9 VASH1 ZNF138	36 interacting genes: BACH2 BICDL2 CALCOCO2 CBY2 CCDC184 CEP76 CTTN DHPS DRAP1 DUX4 ESR1 FAM9B HMBOX1 HOMEZ KXD1 MOCS2 MTUS2 PNMA2 PPP1R27 PSTPIP1 RALY RPS3 SNRPF SORBS2 SREK1IP1 SRSF3 STAC3 TIFA TNFAIP8L1 TRIM37 UBALD1 USO1 VCP ZBTB14 ZBTB7B ZBTB8A
Entrez ID		1725	6133
HPRD ID		02969	04732
Ensembl ID		ENSG00000095059	ENSG00000163682
Uniprot IDs		A0A024R7D0 A0A024R7E9 P49366	P32969 Q53Z07
PDB IDs		1DHS 1RLZ 1ROZ 1RQD 6P4V 6PGR 6WKZ 6WL6 6XXH 6XXI 6XXJ 6XXK 6XXL 6XXM	2CQL 4UG0 4V6X 5AJ0 5LKS 5T2C 6EK0 6IP5 6IP6 6IP8 6LQM 6LSR 6LSS 6LU8 6OLE 6OLF 6OLG 6OLI 6OLZ 6OM0 6OM7 6QZP 6W6L 6XA1 6Y0G 6Y2L 6Y57 6Y6X 6Z6L 6Z6M 6Z6N 6ZM7 6ZME 6ZMI 6ZMO
Enriched GO Terms of Interacting Partners?
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