PRICKLE2 and SMURF2

  • Data Source:
  • HPRD (in vivo)

PRICKLE2

SMURF2

Description prickle planar cell polarity protein 2 SMAD specific E3 ubiquitin protein ligase 2
Image No pdb structure
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Coronary artery calcification ( 23870195)
  • Diisocyanate-induced asthma ( 25918132)
  • Folate pathway vitamin levels ( 19303062)
  • Seborrheic dermatitis ( 29203360)
  • Systemic juvenile idiopathic arthritis ( 27927641)
  • Waist-to-hip ratio adjusted for BMI ( 26426971)
  • Waist-to-hip ratio adjusted for BMI (age <50) ( 26426971)
  • Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971)
  • Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
  • Cardiac troponin-I levels ( 31014085)
  • Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223)
  • Joint mobility (Beighton score) ( 27182965)
  • Lung function (FEV1/FVC) ( 30804560)
  • Lung function (FVC) ( 30804560)
  • Periodontitis (Mean PAL) ( 24024966)
Interacting Genes 3 interacting genes: APP FBXO7 SMURF2 91 interacting genes: ABRAXAS2 ACBD3 ACOX3 AIMP2 ANAPC5 ARHGAP5 ASH2L AXIN1 BTRC CANX CNKSR2 CUEDC1 DAB2 DAZAP2 DGCR2 EGFR EPHA1 FKBP4 FLNB FUBP1 GNG2 HDGFL3 ING2 IRF3 IRF8 ITGB1BP1 KLF5 LAPTM5 LATS1 LMNA MAVS NEK6 NKIRAS1 NRAS PDE4B PPID PRICKLE1 PRICKLE2 RAB13 RAB14 RAB17 RAB22A RAB25 RAN RAP1B RASD2 RASL12 RHOA RHOD RLIM RNF11 RNF111 RNF2 RNF20 RPS27A RRAS2 RTN4IP1 RUNX2 RUNX3 SF3A2 SKIL SMAD1 SMAD2 SMAD3 SMAD5 SMAD6 SMAD7 SMAP1 SNCA SNRNP70 SOCS6 SPART SRSF4 TFPI2 TGFBR1 TMEM139 TNPO3 TOP2A TRAF2 TRAF4 TSSK4 TXNIP UBC UBE2D1 UBE2D2 UBE2D3 UBE2L3 USP15 XPO1 YY1 ZBTB44
Entrez ID 166336 64750
HPRD ID 16342 06901
Ensembl ID ENSG00000163637 ENSG00000108854
Uniprot IDs A0A1X7SBR1 A1LQZ3 Q7Z3G6 Q96DE7 Q9HAU4
PDB IDs 1ZVD 2DJY 2JQZ 2KXQ 2LTZ 6FX4
Enriched GO Terms of Interacting Partners?
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