ACE and BDKRB2

  • Data Source:
  • BioGRID (fluorescent resonance energy transfer)
  • HPRD (in vivo)

ACE

BDKRB2

Description angiotensin I converting enzyme bradykinin receptor B2
Image No pdb structure
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Adventurousness ( 30643258)
  • Alzheimer's disease (late onset) ( 24162737 30820047)
  • Angiotensin-converting enzyme activity ( 20066004)
  • Blood metabolite levels ( 24816252)
  • Blood metabolite ratios ( 24816252)
  • Blood protein levels ( 30072576)
  • Cerebrospinal fluid levels of Alzheimer's disease-related proteins ( 25340798)
  • Diastolic blood pressure ( 28135244 27841878 28739976)
  • Diastolic blood pressure x alcohol consumption interaction (2df test) ( 29912962)
  • Diastolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858)
  • Diastolic blood pressure x smoking status (ever vs never) interaction (2df test) ( 29455858)
  • Medication use (agents acting on the renin-angiotensin system) ( 31015401)
  • Medication use (calcium channel blockers) ( 31015401)
  • Metabolic traits ( 21886157)
  • Metabolite levels ( 23281178)
  • Serum metabolite levels ( 24625756 23093944)
  • Systolic blood pressure ( 27841878 30578418)
  • Systolic blood pressure x alcohol consumption interaction (2df test) ( 29912962)
  • Systolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858)
  • Systolic blood pressure x smoking status (ever vs never) interaction (2df test) ( 29455858)
  • Type 2 diabetes ( 30297969)
  • Cerebrospinal fluid AB1-42 levels ( 28247064)
  • Corneal astigmatism ( 30306274)
  • Gout ( 22179738)
  • Gut microbiota alpha diversity (PD_whole_tree index) ( 33208821)
  • Gut microbiota relative abundance (unclassified genus belonging to the order Clostridiales) ( 33208821)
  • Mumps ( 28928442)
  • Subcutaneous adipose tissue ( 26480920)
Interacting Genes 4 interacting genes: AGTR2 BDKRB2 COMT CSNK2A1 33 interacting genes: AATK ACE AGTR1 AP2M1 CD81 CD82 CLCA4 EFS GNA11 GRK2 GRK3 GRK4 GRK5 GRK6 HERC2 INF2 MPI NIF3L1 NOS1 NOS3 PEX16 PRKCD PTPN11 SLC2A8 SLC35A4 SPG7 SPNS1 SYNE1 SYNGR2 TMEM11 TMEM70 TPI1 USP4
Entrez ID 1636 624
HPRD ID 00108 00213
Ensembl ID ENSG00000159640 ENSG00000168398
Uniprot IDs B4DKH4 P12821 P30411
PDB IDs 1O86 1O8A 1UZE 1UZF 2C6F 2C6N 2IUL 2IUX 2OC2 2XY9 2XYD 2YDM 3BKK 3BKL 3L3N 3NXQ 4APH 4APJ 4BXK 4BZR 4BZS 4C2N 4C2O 4C2P 4C2Q 4C2R 4CA5 4CA6 4UFA 4UFB 5AM8 5AM9 5AMA 5AMB 5AMC 6EN5 6EN6 6F9R 6F9T 6F9U 6F9V 6H5W 6H5X 6QS1 6TT1 6TT3 6TT4 6ZPQ 6ZPT 6ZPU
Enriched GO Terms of Interacting Partners?
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Tagcloud (Difference) ?
Tagcloud (Intersection) ?