BDKRB2 and SLC35A4

Data Source:
BioGRID (two hybrid)

		BDKRB2	SLC35A4
Description		bradykinin receptor B2	solute carrier family 35 member A4
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Endosome Golgi Apparatus Plasma Membrane Integral Component Of Plasma Membrane Intracellular Membrane-bounded Organelle	Golgi Apparatus Integral Component Of Golgi Membrane
	Molecular Function	Protease Binding Phosphatidylinositol Phospholipase C Activity G Protein-coupled Receptor Activity Bradykinin Receptor Activity Protein Binding Type 1 Angiotensin Receptor Binding Protein Heterodimerization Activity	Protein Binding Pyrimidine Nucleotide-sugar Transmembrane Transporter Activity
	Biological Process	Smooth Muscle Contraction Inflammatory Response Cell Surface Receptor Signaling Pathway Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Cytosolic Calcium Ion Concentration Blood Circulation Response To Salt Stress Regulation Of Vasoconstriction Negative Regulation Of Peptidyl-serine Phosphorylation Vasoconstriction Vasodilation Regulation Of Vascular Permeability Arachidonic Acid Secretion Negative Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To Osmotic Stress By P53 Class Mediator	Carbohydrate Transport Pyrimidine Nucleotide-sugar Transmembrane Transport
Pathways		Peptide ligand-binding receptors G alpha (q) signalling events G alpha (i) signalling events
Drugs		Anatibant Icatibant Labradimil
Diseases
GWAS		Cerebrospinal fluid AB1-42 levels ( 28247064) Corneal astigmatism ( 30306274) Gout ( 22179738) Gut microbiota alpha diversity (PD_whole_tree index) ( 33208821) Gut microbiota relative abundance (unclassified genus belonging to the order Clostridiales) ( 33208821) Mumps ( 28928442) Subcutaneous adipose tissue ( 26480920)	Serum immune biomarker levels ( 32066700)
Interacting Genes		33 interacting genes: AATK ACE AGTR1 AP2M1 CD81 CD82 CLCA4 EFS GNA11 GRK2 GRK3 GRK4 GRK5 GRK6 HERC2 INF2 MPI NIF3L1 NOS1 NOS3 PEX16 PRKCD PTPN11 SLC2A8 SLC35A4 SPG7 SPNS1 SYNE1 SYNGR2 TMEM11 TMEM70 TPI1 USP4	23 interacting genes: BDKRB2 COMT CPLX4 CREB3L1 CYB5R3 EBAG9 ERGIC3 FAM209A FRMD3 GGT7 GJA8 GPR152 HERPUD2 LMNA SCN3B SLC10A4 SLC13A4 SYT2 TMEM14B TMEM154 TMEM237 TMEM52B YIPF4
Entrez ID		624	113829
HPRD ID		00213	11574
Ensembl ID		ENSG00000168398	ENSG00000176087
Uniprot IDs		P30411	Q96G79
PDB IDs
Enriched GO Terms of Interacting Partners?
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