BDKRB2 and SLC2A8

Data Source:
BioGRID (two hybrid)

		BDKRB2	SLC2A8
Description		bradykinin receptor B2	solute carrier family 2 member 8
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Endosome Golgi Apparatus Plasma Membrane Integral Component Of Plasma Membrane Intracellular Membrane-bounded Organelle	Lysosomal Membrane Plasma Membrane Integral Component Of Plasma Membrane Synaptic Vesicle Clathrin-coated Vesicle Membrane
	Molecular Function	Protease Binding Phosphatidylinositol Phospholipase C Activity G Protein-coupled Receptor Activity Bradykinin Receptor Activity Protein Binding Type 1 Angiotensin Receptor Binding Protein Heterodimerization Activity	Fructose Transmembrane Transporter Activity Glucose Transmembrane Transporter Activity Glucose Binding Dehydroascorbic Acid Transmembrane Transporter Activity
	Biological Process	Smooth Muscle Contraction Inflammatory Response Cell Surface Receptor Signaling Pathway Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Cytosolic Calcium Ion Concentration Blood Circulation Response To Salt Stress Regulation Of Vasoconstriction Negative Regulation Of Peptidyl-serine Phosphorylation Vasoconstriction Vasodilation Regulation Of Vascular Permeability Arachidonic Acid Secretion Negative Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To Osmotic Stress By P53 Class Mediator	Response To Hypoxia Carbohydrate Metabolic Process Male Meiosis I Insulin Receptor Signaling Pathway Hexose Transmembrane Transport Fructose Transmembrane Transport Membrane Organization Dehydroascorbic Acid Transport Glucose Transmembrane Transport
Pathways		Peptide ligand-binding receptors G alpha (q) signalling events G alpha (i) signalling events	Cellular hexose transport Cargo recognition for clathrin-mediated endocytosis Clathrin-mediated endocytosis
Drugs		Anatibant Icatibant Labradimil
Diseases
GWAS		Cerebrospinal fluid AB1-42 levels ( 28247064) Corneal astigmatism ( 30306274) Gout ( 22179738) Gut microbiota alpha diversity (PD_whole_tree index) ( 33208821) Gut microbiota relative abundance (unclassified genus belonging to the order Clostridiales) ( 33208821) Mumps ( 28928442) Subcutaneous adipose tissue ( 26480920)	Bipolar disorder ( 20351715) Major depressive disorder ( 27777418) Metabolite levels (HVA) ( 23319000)
Interacting Genes		33 interacting genes: AATK ACE AGTR1 AP2M1 CD81 CD82 CLCA4 EFS GNA11 GRK2 GRK3 GRK4 GRK5 GRK6 HERC2 INF2 MPI NIF3L1 NOS1 NOS3 PEX16 PRKCD PTPN11 SLC2A8 SLC35A4 SPG7 SPNS1 SYNE1 SYNGR2 TMEM11 TMEM70 TPI1 USP4	4 interacting genes: AP1B1 AP2A2 AP2B1 BDKRB2
Entrez ID		624	29988
HPRD ID		00213	05580
Ensembl ID		ENSG00000168398	ENSG00000136856
Uniprot IDs		P30411	A0A024R871 A0A087WT42 Q5VVV9 Q8WZ05 Q9NY64
PDB IDs
Enriched GO Terms of Interacting Partners?
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