CUX1 and SATB1

Data Source:
HPRD (in vivo, in vitro)

		CUX1	SATB1
Description		cut like homeobox 1	SATB homeobox 1
Image		No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Chromatin Nucleus Nucleoplasm Golgi Apparatus Cytosol	Chromatin Nucleus Nucleoplasm Nuclear Matrix Nuclear Body PML Body
	Molecular Function	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Protein-macromolecule Adaptor Activity Sequence-specific DNA Binding Sequence-specific Double-stranded DNA Binding	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific Double-stranded DNA Binding Protein Binding Sequence-specific DNA Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Retrograde Transport, Vesicle Recycling Within Golgi Regulation Of Transcription By RNA Polymerase II Multicellular Organism Development Positive Regulation Of Dendrite Morphogenesis	Negative Regulation Of Transcription By RNA Polymerase II Chromatin Organization Chromatin Remodeling Regulation Of Transcription By RNA Polymerase II Viral Process
Pathways		Signaling by cytosolic FGFR1 fusion mutants Signaling by FGFR1 in disease Intra-Golgi traffic	Apoptotic cleavage of cellular proteins SUMOylation of chromatin organization proteins
Drugs
Diseases
GWAS		Attention deficit hyperactivity disorder symptom score ( 27663945) Basal cell carcinoma ( 31174203 27539887) Breast cancer ( 29059683) Cerebellum cortex volume ( 31530798) Chronotype ( 30696823) Eosinophil counts ( 32888494) Eosinophil percentage of white cells ( 32888494) HDL cholesterol levels ( 32203549) High light scatter reticulocyte count ( 32888494) High light scatter reticulocyte percentage of red cells ( 32888494) Intelligence (MTAG) ( 29326435) Keratinocyte cancer (MTAG) ( 31174203) Mean platelet volume ( 32888494 27863252) Morning person ( 30696823) Platelet distribution width ( 32888494 27863252) Plateletcrit ( 32888494 27863252) Response to antidepressants ( 22584459) Reticulocyte count ( 32888494 27863252) Reticulocyte fraction of red cells ( 32888494 27863252) Vertical cup-disc ratio (multi-trait analysis) ( 31959993)	Adventurousness ( 30643258) Chronic mucus hypersecretion ( 24714607) Familial lung adenocarcinoma ( 29924316) General risk tolerance (MTAG) ( 30643258) Itch intensity from mosquito bite ( 28199695) Left-handedness ( 32989287) Parkinson's disease ( 28892059) Parkinson's disease or first degree relation to individual with Parkinson's disease ( 31701892) Platelet count ( 22139419) Response to fenofibrate (HDL cholesterol levels) ( 27002377) SjÃ¶gren's syndrome ( 24097067)
Interacting Genes		21 interacting genes: BIN1 CA12 CCNA1 CDC25A CDK1 CDK7 CREBBP CTSL CYTH2 EHMT2 ELAC2 GOLGA5 HMGB1 KAT2B MAX RB1 RECQL5 SATB1 SDC3 SUMO2 TLE4	23 interacting genes: BAZ1A CASP6 CBX4 CHD3 CUX1 EP300 GATA3 HDAC1 KAT2B MEOX2 MTA2 PIAS1 PIAS3 PIAS4 POLR2J SIRT1 SMARCA5 SPG21 SUMO1 SUMO1P1 TOPORS UBE2I UBR5
Entrez ID		1523	6304
HPRD ID		00295	03647
Ensembl ID		ENSG00000257923	ENSG00000182568
Uniprot IDs		P39880 Q13948 Q3LIA3	A0A024R2H1 Q01826
PDB IDs			1YSE 2L1P 2MW8 2O49 2O4A 3NZL 3TUO 6LFF
Enriched GO Terms of Interacting Partners?
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