CSNK1D and TRIM9

Data Source:
BioGRID (two hybrid)

		CSNK1D	TRIM9
Description		casein kinase 1 delta	tripartite motif containing 9
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GO Annotations	Cellular Component	Golgi Membrane Nucleus Nucleoplasm Cytoplasm Golgi Apparatus Centrosome Spindle Cytosol Spindle Microtubule Plasma Membrane Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane Ciliary Basal Body Perinuclear Region Of Cytoplasm	Cytoplasm Cytoskeleton Synaptic Vesicle Dendrite Presynaptic Cytosol
	Molecular Function	Protein Kinase Activity Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Cadherin Binding Tau-protein Kinase Activity Protein Serine Kinase Activity Protein Threonine Kinase Activity	SNARE Binding Protein Binding Zinc Ion Binding Protein Domain Specific Binding Protein Homodimerization Activity Ubiquitin Protein Ligase Activity
	Biological Process	G2/M Transition Of Mitotic Cell Cycle Positive Regulation Of Protein Phosphorylation Protein Phosphorylation Microtubule Nucleation Golgi Organization Regulation Of G2/M Transition Of Mitotic Cell Cycle Wnt Signaling Pathway Peptidyl-serine Phosphorylation Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Circadian Regulation Of Gene Expression Protein Localization To Golgi Apparatus Regulation Of Circadian Rhythm COPII Vesicle Coating Spindle Assembly Protein Localization To Cilium Protein Localization To Centrosome Positive Regulation Of Canonical Wnt Signaling Pathway Ciliary Basal Body-plasma Membrane Docking Positive Regulation Of Wnt-mediated Midbrain Dopaminergic Neuron Differentiation Non-motile Cilium Assembly Positive Regulation Of Non-canonical Wnt Signaling Pathway	Synaptic Vesicle Exocytosis Protein Ubiquitination Negative Regulation Of SNARE Complex Assembly Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Calcium Ion-dependent Exocytosis
Pathways		COPII-mediated vesicle transport Regulation of PLK1 Activity at G2/M Transition Loss of Nlp from mitotic centrosomes Recruitment of mitotic centrosome proteins and complexes Loss of proteins required for interphase microtubule organization from the centrosome Recruitment of NuMA to mitotic centrosomes Circadian Clock Anchoring of the basal body to the plasma membrane Major pathway of rRNA processing in the nucleolus and cytosol AURKA Activation by TPX2	Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS			Coronary artery calcified atherosclerotic plaque (130 HU threshold) in type 2 diabetes ( 29221444) Psychosis (atypical) ( 24132900) Response to cyclophosphamide in systemic lupus erythematosus with lupus nephritis ( 26980576) Urate levels (BMI interaction) ( 25811787)
Interacting Genes		41 interacting genes: AKAP9 APP ARFGAP1 ATM BACE1 BRCA1 CCDC14 CDK5 CTNNB1 DRICH1 DVL1 DVL3 EVI5 GJA1 HIF1A IKZF4 JPT2 KDR LURAP1 LZTS2 MAPT PAK5 PER1 PER2 PER3 PPP1R14A PPP5C PSEN2 PTPRD RAB1A SMAD2 SMAD3 SMURF1 SNAPIN SNCA TP53 TRIM3 TRIM9 YWHAZ ZBTB8A ZNF618	32 interacting genes: AP3M1 BTRC CHFR CSNK1D CWF19L2 DTNBP1 DTX3L EVL EXOC1 FAM124B FAM90A1 GFM2 LONRF1 MDM2 MNAT1 MUL1 NCF1 NFKBID NTAQ1 PCGF3 RNF166 RPL4P5 SNAP25 SPG21 TRIM27 TRIM46 TRIM8 TSSK3 USP2 USP21 UTP25 VASP
Entrez ID		1453	114088
HPRD ID		02920	05947
Ensembl ID		ENSG00000141551	ENSG00000100505
Uniprot IDs		P48730	Q9C026
PDB IDs		3UYS 3UYT 3UZP 4HGT 4HNF 4KB8 4KBA 4KBC 4KBK 4TN6 4TW9 4TWC 5IH4 5IH5 5IH6 5MQV 5OKT 5W4W 6F1W 6F26 6GZM 6HMP 6HMR 6PXN 6PXO 6PXP 6RCG 6RCH 6RU6 6RU7 6RU8	2DB8
Enriched GO Terms of Interacting Partners?
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