TRIM9 and PCGF3

Data Source:
BioGRID (two hybrid)

		TRIM9	PCGF3
Description		tripartite motif containing 9	polycomb group ring finger 3
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytoskeleton Synaptic Vesicle Dendrite Presynaptic Cytosol	X Chromosome Nucleus Nucleoplasm PcG Protein Complex PRC1 Complex
	Molecular Function	SNARE Binding Protein Binding Zinc Ion Binding Protein Domain Specific Binding Protein Homodimerization Activity Ubiquitin Protein Ligase Activity	Protein Binding Metal Ion Binding
	Biological Process	Synaptic Vesicle Exocytosis Protein Ubiquitination Negative Regulation Of SNARE Complex Assembly Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Calcium Ion-dependent Exocytosis	Regulation Of Transcription By RNA Polymerase II Histone H2A-K119 Monoubiquitination Inactivation Of X Chromosome By Genetic Imprinting
Pathways		Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS		Coronary artery calcified atherosclerotic plaque (130 HU threshold) in type 2 diabetes ( 29221444) Psychosis (atypical) ( 24132900) Response to cyclophosphamide in systemic lupus erythematosus with lupus nephritis ( 26980576) Urate levels (BMI interaction) ( 25811787)	General cognitive ability ( 29844566) Granulocyte count ( 27863252) Granulocyte percentage of myeloid white cells ( 27863252) Heel bone mineral density ( 30598549) Hemostatic factors and hematological phenotypes ( 22443383) Intelligence (MTAG) ( 29326435) Itch intensity from mosquito bite adjusted by bite size ( 28199695) Monocyte percentage of white cells ( 32888494 27863252) Myeloid white cell count ( 27863252) Neutrophil count ( 32888494 27863252) Neutrophil percentage of white cells ( 32888494) Sum basophil neutrophil counts ( 27863252) Sum neutrophil eosinophil counts ( 27863252) Type 2 diabetes ( 30297969 32499647) White blood cell count ( 32888494 27863252)
Interacting Genes		32 interacting genes: AP3M1 BTRC CHFR CSNK1D CWF19L2 DTNBP1 DTX3L EVL EXOC1 FAM124B FAM90A1 GFM2 LONRF1 MDM2 MNAT1 MUL1 NCF1 NFKBID NTAQ1 PCGF3 RNF166 RPL4P5 SNAP25 SPG21 TRIM27 TRIM46 TRIM8 TSSK3 USP2 USP21 UTP25 VASP	15 interacting genes: BCOR BCORL1 BMI1 CBX6 DZIP3 HNRNPK PHC1 PHC2 RING1 RNF2 TRIM55 TRIM63 TRIM9 UBE2C UBE2D3
Entrez ID		114088	10336
HPRD ID		05947	11515
Ensembl ID		ENSG00000100505	ENSG00000185619
Uniprot IDs		Q9C026	B3KQ06 B3KWT8 B4DTN5 Q3KNV8
PDB IDs		2DB8
Enriched GO Terms of Interacting Partners?
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