COL8A2 and BSND

Data Source:
BioGRID (two hybrid)

		COL8A2	BSND
Description		collagen type VIII alpha 2 chain	barttin CLCNK type accessory subunit beta
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Region Collagen Trimer Basement Membrane Extracellular Space Endoplasmic Reticulum Lumen Extracellular Matrix Collagen-containing Extracellular Matrix	Cytoplasm Plasma Membrane Integral Component Of Plasma Membrane Basolateral Plasma Membrane Protein-containing Complex
	Molecular Function	Extracellular Matrix Structural Constituent Extracellular Matrix Structural Constituent Conferring Tensile Strength Protein-macromolecule Adaptor Activity	Chloride Channel Activity Protein Binding Chloride Channel Regulator Activity
	Biological Process	Angiogenesis Extracellular Matrix Organization Camera-type Eye Morphogenesis Epithelial Cell Proliferation Cell-cell Adhesion	Chloride Transport Ion Transmembrane Transport Chloride Transmembrane Transport
Pathways		Collagen degradation Collagen degradation Collagen biosynthesis and modifying enzymes Assembly of collagen fibrils and other multimeric structures Integrin cell surface interactions Collagen chain trimerization	Stimuli-sensing channels
Drugs
Diseases		Posterior polymorphous corneal dystrophy (PPCD) Fuchs corneal dystrophy (FECD); Fuchs endothelial corneal dystrophy	Bartter syndrome
GWAS		Central corneal thickness ( 32528159 29760442) Corneal structure ( 23291589) Early spontaneous preterm birth ( 31194736) Intraocular pressure ( 29617998 29785010 31959993)	Allergic rhinitis ( 25085501) Carotid intima media thickness x smoking interaction ( 32117412) Coronary artery disease ( 32469254 33020668) Medication use (HMG CoA reductase inhibitors) ( 31015401) Mitochondrial DNA copy number ( 30704525)
Interacting Genes		18 interacting genes: ARL13B ATP6V0E1 BSND COL8A1 CREB3L1 CYB5R3 DARS2 FAM209A FNDC9 GPR152 GPX8 LMNA MUC1 PEX12 PLEKHO1 SGTA TFAM TMX2	28 interacting genes: ADIPOQ APOL2 APP ARFIP1 BMP10 CDIPT CERT1 COL4A5 COL8A2 CSGALNACT2 CTSA ECPAS FATE1 GAD2 IGFBP5 JAGN1 MYG1 PBX3 PLSCR2 PTPN9 SLC30A8 SPG21 STX8 TBRG4 THAP4 TMEM60 VAMP3 ZFPL1
Entrez ID		1296	7809
HPRD ID		08347	05914
Ensembl ID		ENSG00000171812	ENSG00000162399
Uniprot IDs		E9PP49 P25067	Q5VU50 Q8WZ55
PDB IDs
Enriched GO Terms of Interacting Partners?
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