COL4A1 and COL4A2

  • Data Source:
  • BioGRID (x-ray crystallography)
  • HPRD (in vitro)

COL4A1

COL4A2

Description collagen type IV alpha 1 chain collagen type IV alpha 2 chain
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Apolipoprotein B levels ( 32203549)
  • Arterial stiffness ( 31070453)
  • Arterial stiffness index ( 31235810)
  • Blood urea nitrogen levels ( 31152163)
  • Coronary artery calcification ( 22144573)
  • Coronary artery disease ( 32469254 29212778 24262325 26343387 33020668)
  • Coronary artery disease (myocardial infarction, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease) ( 28714975)
  • Coronary heart disease ( 21378990)
  • Diastolic blood pressure ( 27841878)
  • Glomerular filtration rate ( 29403010)
  • Intake of sweets ( 31005972)
  • Ischemic stroke (small-vessel) ( 29531354)
  • LDL cholesterol ( 30275531)
  • LDL cholesterol levels ( 32203549)
  • Low density lipoprotein cholesterol levels ( 32154731)
  • Maximum retinal arteriolar tortuosity ( 31597446)
  • Middle temporal gyrus volume ( 31530798)
  • Myocardial infarction ( 26343387)
  • Night sleep phenotypes ( 27126917)
  • Non-lobar intracerebral hemorrhage ( 31430377)
  • Non-lobar intracerebral hemorrhage (MTAG) ( 31430377)
  • Periventricular white matter hyperintensities ( 32517579)
  • Platelet count ( 32888494)
  • Plateletcrit ( 32888494)
  • Retinal arteriolar tortuosity ( 31597446)
  • Serum bilirubin levels x sex interaction in metabolic syndrome ( 30621171)
  • Total cholesterol levels ( 30275531)
  • Triglyceride levels ( 32203549)
  • White matter hyperintensities ( 32358547)
  • White matter hyperintensity burden ( 25663218)
Interacting Genes 27 interacting genes: ACHE APCS APP BMP3 CD93 COL4A2 COL7A1 DCN DISC1 FBLN2 FN1 HABP2 MAG MATN2 MMP9 NID1 NID2 OSM PDGFA PDGFB SAA1 SAA2 SAA4 SERPINE2 SMAD1 TGFBI THBS1 24 interacting genes: ANTXR2 ANXA7 APP ATF7IP BGN BMP3 CD93 COL4A1 CSNK2B DAZAP2 FBLN2 FN1 HABP2 MATN2 MMP9 OSM SAA1 SERPINE2 SKIL SMN1 TENT5A TGFBI TK1 VHL
Entrez ID 1282 1284
HPRD ID 00359 00355
Ensembl ID ENSG00000187498 ENSG00000134871
Uniprot IDs A5PKV2 P02462 A0A024RDW8 P08572
PDB IDs 1LI1 5NAX 5NAY 6MPX 1LI1 5NAX 5NB2 6MPX
Enriched GO Terms of Interacting Partners?
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