RN7SK and HEXIM1

Data Source:
BioGRID (affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology)

		RN7SK	HEXIM1
Description		RNA component of 7SK nuclear ribonucleoprotein	HEXIM P-TEFb complex subunit 1
Image		No pdb structure
GO Annotations	Cellular Component	7SK SnRNP	Nucleus Nucleoplasm Cytoplasm Intracellular Membrane-bounded Organelle 7SK SnRNP
	Molecular Function		Protein Kinase Inhibitor Activity Cyclin-dependent Protein Serine/threonine Kinase Inhibitor Activity Protein Binding SnRNA Binding Identical Protein Binding 7SK SnRNA Binding P-TEFb Complex Binding
	Biological Process	Negative Regulation Of Transcription Elongation From RNA Polymerase II Promoter	Negative Regulation Of Transcription By RNA Polymerase II Activation Of Innate Immune Response Heart Development Negative Regulation Of Viral Transcription Negative Regulation Of Transcription Elongation From RNA Polymerase II Promoter Innate Immune Response Negative Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Signal Transduction By P53 Class Mediator
Pathways
Drugs
Diseases
GWAS		Staphylococcus aureus nasal carriage (intermittent) ( 26569114)	Asthma ( 31959851 31619474) Brain morphology (MOSTest) ( 32665545) Craniofacial microsomia ( 26853712) Insomnia ( 32332799) Male-pattern baldness ( 28196072) Systolic blood pressure ( 19430483)
Interacting Genes		6 interacting genes: CCNT1 CDK9 HEXIM1 HMGA1 LARP7 MEPCE	11 interacting genes: CCNT1 CCNT2 CDK9 EGFR ESR1 HEXIM2 RELA RN7SK TERF1 TERF2 UBE2O
Entrez ID		125050	10614
HPRD ID			09544
Ensembl ID		ENSG00000202198	ENSG00000186834
Uniprot IDs			O94992
PDB IDs			2GD7 3S9G
Enriched GO Terms of Interacting Partners?
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