HEXIM1 and RN7SK

Data Source:
BioGRID (affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology)

		HEXIM1	RN7SK
Description		HEXIM P-TEFb complex subunit 1	RNA component of 7SK nuclear ribonucleoprotein
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Intracellular Membrane-bounded Organelle 7SK SnRNP	7SK SnRNP
	Molecular Function	Protein Kinase Inhibitor Activity Cyclin-dependent Protein Serine/threonine Kinase Inhibitor Activity Protein Binding SnRNA Binding Identical Protein Binding 7SK SnRNA Binding P-TEFb Complex Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Activation Of Innate Immune Response Heart Development Negative Regulation Of Viral Transcription Negative Regulation Of Transcription Elongation From RNA Polymerase II Promoter Innate Immune Response Negative Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Signal Transduction By P53 Class Mediator	Negative Regulation Of Transcription Elongation From RNA Polymerase II Promoter
Pathways
Drugs
Diseases
GWAS		Asthma ( 31959851 31619474) Brain morphology (MOSTest) ( 32665545) Craniofacial microsomia ( 26853712) Insomnia ( 32332799) Male-pattern baldness ( 28196072) Systolic blood pressure ( 19430483)	Staphylococcus aureus nasal carriage (intermittent) ( 26569114)
Interacting Genes		11 interacting genes: CCNT1 CCNT2 CDK9 EGFR ESR1 HEXIM2 RELA RN7SK TERF1 TERF2 UBE2O	6 interacting genes: CCNT1 CDK9 HEXIM1 HMGA1 LARP7 MEPCE
Entrez ID		10614	125050
HPRD ID		09544
Ensembl ID		ENSG00000186834	ENSG00000202198
Uniprot IDs		O94992
PDB IDs		2GD7 3S9G
Enriched GO Terms of Interacting Partners?
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