DHRS1 and HTR6

Data Source:
BioGRID (two hybrid)

		DHRS1	HTR6
Description		dehydrogenase/reductase 1	5-hydroxytryptamine receptor 6
Image			No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum	Plasma Membrane Integral Component Of Plasma Membrane Cilium Dendrite Synapse
	Molecular Function	Protein Binding Oxidoreductase Activity	Histamine Receptor Activity G Protein-coupled Serotonin Receptor Activity Protein Binding Neurotransmitter Receptor Activity
	Biological Process		G Protein-coupled Receptor Signaling Pathway G Protein-coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger Chemical Synaptic Transmission Cerebral Cortex Cell Migration Positive Regulation Of TOR Signaling G Protein-coupled Serotonin Receptor Signaling Pathway
Pathways			Serotonin receptors G alpha (s) signalling events ADORA2B mediated anti-inflammatory cytokines production
Drugs			Ziprasidone Amitriptyline Olanzapine Clozapine Loxapine Imipramine Chlorpromazine Haloperidol Amoxapine Paroxetine Cyclobenzaprine Ergoloid mesylate Doxepin Quetiapine Aripiprazole Chlorprothixene Dimethyltryptamine Lysergic acid diethylamide Iloperidone SGS518 PRX-07034 SUVN-502 Sertindole Mianserin Asenapine Zotepine Setiptiline Dihydroergocornine Gilteritinib Tiapride Dihydroergocristine Aripiprazole lauroxil
Diseases
GWAS		Parent of origin effect on language impairment (paternal) ( 24571439)	Chronotype ( 26955885 27494321) Morning person ( 30696823) Morning vs. evening chronotype ( 26955885 27494321)
Interacting Genes		29 interacting genes: BNIP2 DIABLO HTR6 KRT34 KRTAP1-1 KRTAP1-3 KRTAP10-3 KRTAP10-8 KRTAP10-9 KRTAP11-1 KRTAP12-1 KRTAP12-2 KRTAP12-3 KRTAP3-2 KRTAP4-1 KRTAP4-11 KRTAP5-1 KRTAP5-2 KRTAP5-9 KRTAP6-2 KRTAP6-3 KRTAP9-8 LCE2B LHX4 MDFI MTUS2 NBPF19 NOTCH2NLA PLSCR1	31 interacting genes: ABCA2 ACTB AIP AKR1A1 AP2M1 AP4S1 ATXN10 CHN1 CMSS1 COPS5 DDRGK1 DHRS1 EIF4A3 FYN GNAQ GNAS HDGFL2 IDS MAP1B NF1 NRXN3 PARP8 RUNDC3A SCHIP1 SLC6A1 SRRT SYT5 THY1 TMEM98 TTYH1 UQCRFS1
Entrez ID		115817	3362
HPRD ID		09914	03066
Ensembl ID		ENSG00000157379	ENSG00000158748
Uniprot IDs		Q96LJ7	P50406
PDB IDs		2QQ5
Enriched GO Terms of Interacting Partners?
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