MBD6 and ASXL2

Data Source:
BioGRID (affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid)

		MBD6	ASXL2
Description		methyl-CpG binding domain protein 6	ASXL transcriptional regulator 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Fibrillar Center Nucleus Nucleoplasm Chromosome Chromocenter	Nucleoplasm PR-DUB Complex
	Molecular Function	DNA Binding Chromatin Binding Protein Binding	DNA Binding Chromatin Binding Peroxisome Proliferator Activated Receptor Binding Metal Ion Binding
	Biological Process	Protein Deubiquitination	Transcription, DNA-templated Animal Organ Morphogenesis Positive Regulation Of Lipid Storage Protein Deubiquitination Positive Regulation Of Peroxisome Proliferator Activated Receptor Signaling Pathway Positive Regulation Of Fat Cell Differentiation Positive Regulation Of Transcription By RNA Polymerase II
Pathways		UCH proteinases	UCH proteinases
Drugs
Diseases
GWAS		Brain morphology (MOSTest) ( 32665545)	Decreased low contrast letter acuity in multiple sclerosis ( 31289819) Heel bone mineral density ( 30598549) Hemoglobin levels ( 32327693) High light scatter reticulocyte count ( 32888494) High light scatter reticulocyte percentage of red cells ( 32888494) Immature fraction of reticulocytes ( 32888494) Multiple myeloma ( 26007630) Multiple myeloma and monoclonal gammopathy ( 26007630) Red cell distribution width ( 32888494) Reticulocyte count ( 32888494) Reticulocyte fraction of red cells ( 32888494) Thyroid stimulating hormone levels ( 32769997) Triglyceride levels ( 32203549)
Interacting Genes		5 interacting genes: ASXL2 ATXN1L DUSP12 NCK2 RBM10	7 interacting genes: APP MBD6 PRPF40A UBC UBE2E1 UBE2E2 UBE2E3
Entrez ID		114785	55252
HPRD ID		11296	10676
Ensembl ID		ENSG00000166987	ENSG00000143970
Uniprot IDs		A0A024RBA3 Q6P0P0 Q96DN6	Q76L83
PDB IDs
Enriched GO Terms of Interacting Partners?
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