ASXL2 and UBE2E1

  • Data Source:
  • BioGRID (enzymatic study)

ASXL2

UBE2E1

Description ASXL transcriptional regulator 2 ubiquitin conjugating enzyme E2 E1
Image No pdb structure
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Decreased low contrast letter acuity in multiple sclerosis ( 31289819)
  • Heel bone mineral density ( 30598549)
  • Hemoglobin levels ( 32327693)
  • High light scatter reticulocyte count ( 32888494)
  • High light scatter reticulocyte percentage of red cells ( 32888494)
  • Immature fraction of reticulocytes ( 32888494)
  • Multiple myeloma ( 26007630)
  • Multiple myeloma and monoclonal gammopathy ( 26007630)
  • Red cell distribution width ( 32888494)
  • Reticulocyte count ( 32888494)
  • Reticulocyte fraction of red cells ( 32888494)
  • Thyroid stimulating hormone levels ( 32769997)
  • Triglyceride levels ( 32203549)
Interacting Genes 7 interacting genes: APP MBD6 PRPF40A UBC UBE2E1 UBE2E2 UBE2E3 114 interacting genes: ARIH2 ASXL2 BARD1 BIRC7 BIRC8 BRCA1 CADPS2 CBL CBWD5 CHFR CNOT4 CUL3 DTX1 DTX3 DTX3L DZIP3 EPS15 F12 FBXL17 FBXO2 FBXO7 H3C1 H4C1 HDAC6 IPO11 ITCH JADE1 LRSAM1 MAP3K1 MARCHF3 MARCHF5 MARCHF7 MDM2 MGRN1 MID1 MKRN3 MUL1 NEDD4 NEDD4L NHLRC1 PAEP PBX2 POLL POLM PRKN RBX1 RELA RFWD3 RLIM RMND5B RNF10 RNF103 RNF11 RNF111 RNF114 RNF115 RNF122 RNF128 RNF13 RNF130 RNF14 RNF150 RNF152 RNF165 RNF166 RNF167 RNF168 RNF169 RNF181 RNF185 RNF2 RNF20 RNF26 RNF31 RNF4 RNF40 RNF43 RNF5 RNF8 STUB1 TOPORS TRAF6 TRIM17 TRIM2 TRIM21 TRIM23 TRIM27 TRIM28 TRIM29 TRIM3 TRIM32 TRIM33 TRIM37 TRIM38 TRIM39 TRIM45 TRIM50 TRIM69 TRIM7 UBA1 UBA7 UBASH3B UBE2G1 UBE3A UBOX5 UBR7 UFM1 USP7 UVSSA WWP2 XIAP ZNRF1 ZNRF2 ZNRF4
Entrez ID 55252 7324
HPRD ID 10676 04225
Ensembl ID ENSG00000143970 ENSG00000170142
Uniprot IDs Q76L83 A0A024R2K3 B7Z306 P51965
PDB IDs 1XR9 3BZH 4JJQ 5LBN 6FGA
Enriched GO Terms of Interacting Partners?
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