ASXL2 and UBE2E3

  • Data Source:
  • BioGRID (enzymatic study)

ASXL2

UBE2E3

Description ASXL transcriptional regulator 2 ubiquitin conjugating enzyme E2 E3
Image No pdb structure No pdb structure
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Decreased low contrast letter acuity in multiple sclerosis ( 31289819)
  • Heel bone mineral density ( 30598549)
  • Hemoglobin levels ( 32327693)
  • High light scatter reticulocyte count ( 32888494)
  • High light scatter reticulocyte percentage of red cells ( 32888494)
  • Immature fraction of reticulocytes ( 32888494)
  • Multiple myeloma ( 26007630)
  • Multiple myeloma and monoclonal gammopathy ( 26007630)
  • Red cell distribution width ( 32888494)
  • Reticulocyte count ( 32888494)
  • Reticulocyte fraction of red cells ( 32888494)
  • Thyroid stimulating hormone levels ( 32769997)
  • Triglyceride levels ( 32203549)
Interacting Genes 7 interacting genes: APP MBD6 PRPF40A UBC UBE2E1 UBE2E2 UBE2E3 95 interacting genes: ACVR1 ARID3A ARIH2 ARRDC3 ASXL2 ATXN1 BARD1 BRCA1 CADPS2 CBL CHFR CHUK CNOT4 CUL1 CUL3 CUL4A DAZAP2 DTX3 DTX3L DZIP3 H3C1 H4C1 HERC4 HTT IPO11 ITCH KLHL42 MARCHF5 MDM2 MID1 MID2 MKRN3 MUL1 NEDD4L NFKBIA OTUB1 PGPEP1 PICK1 PJA1 PRKN RANGAP1 RBX1 RC3H2 RCBTB1 RFWD3 RING1 RMND5B RNF11 RNF111 RNF114 RNF115 RNF126 RNF13 RNF130 RNF14 RNF150 RNF165 RNF166 RNF167 RNF181 RNF185 RNF2 RNF25 RNF31 RNF4 RNF43 RNF5 RNF8 SAE1 SIAH1 SPOP STUB1 TGFBR1 TRIM2 TRIM27 TRIM32 TRIM37 TRIM38 TRIM39 TRIM45 TRIM50 TRIM54 TRIM55 TRIM62 TRIM63 TTC3 UBA1 UBC UBOX5 UFM1 WBP2 WWP2 ZNF746 ZNRF1 ZNRF4
Entrez ID 55252 10477
HPRD ID 10676 05000
Ensembl ID ENSG00000143970 ENSG00000170035
Uniprot IDs Q76L83 Q969T4 R4GNG6
PDB IDs
Enriched GO Terms of Interacting Partners?
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