RASSF1 and NUDT10

Data Source:
HPRD (two hybrid)

		RASSF1	NUDT10
Description		Ras association domain family member 1	nudix hydrolase 10
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GO Annotations	Cellular Component	Spindle Pole Nucleus Cytoplasm Microtubule Organizing Center Microtubule Microtubule Cytoskeleton	Nucleus Cytoplasm Cytosol
	Molecular Function	Protein Binding Zinc Ion Binding	Endopolyphosphatase Activity Protein Binding Diphosphoinositol-polyphosphate Diphosphatase Activity Bis(5'-adenosyl)-hexaphosphatase Activity Bis(5'-adenosyl)-pentaphosphatase Activity Metal Ion Binding M7G(5')pppN Diphosphatase Activity Inositol Diphosphate Tetrakisphosphate Diphosphatase Activity Inositol Diphosphate Pentakisphosphate Diphosphatase Activity
	Biological Process	Cell Cycle Arrest Signal Transduction Ras Protein Signal Transduction Regulation Of Microtubule Cytoskeleton Organization	Inositol Phosphate Metabolic Process Diphosphoinositol Polyphosphate Metabolic Process Diadenosine Pentaphosphate Catabolic Process Diadenosine Hexaphosphate Catabolic Process Adenosine 5'-(hexahydrogen Pentaphosphate) Catabolic Process
Pathways			Synthesis of pyrophosphates in the cytosol
Drugs
Diseases		Non-small cell lung cancer Bladder cancer Nasopharyngeal cancer
GWAS		Basophil percentage of white cells ( 32888494) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (MOSTest) ( 32665545) High light scatter reticulocyte count ( 32888494) Reticulocyte count ( 32888494) Reticulocyte fraction of red cells ( 32888494) Schizophrenia ( 28991256 30285260) Sleep duration (short sleep) ( 30846698) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545)	Prostate cancer ( 18264097 18264098)
Interacting Genes		70 interacting genes: AKT1 ARAF ATM ATP2B4 ATR ATRX AURKA AURKB BRAF C7orf25 C8orf33 CCND2 CCNE1 CDC20 CDK4 CDK6 CDKN2A CDKN2B CLNK CNKSR1 DAXX DDB1 E4F1 EPHA2 ERBB2 EXOSC8 FGFR4 FZR1 GLIS2 GRM1 HRAS IGFBP5 KAT2A KCNE3 KDELR2 KDM1A LATS2 MAP1B MAP1S MAP2K3 MAP2K6 MAPK8 MDM2 MET MOAP1 MST1 MYC NF2 NUDT10 PRKDC RAF1 RASSF5 RELA RHOA RHOU SAV1 SMARCA4 STK11 STK3 STK4 SUV39H1 SUV39H2 TEAD2 TERT TNFRSF10A TNFRSF1A TSC1 TUBB TUBG1 XPA	8 interacting genes: HSF2BP MTUS2 PDLIM7 RASSF1 REL SNAPC5 TCF4 TRIM8
Entrez ID		11186	170685
HPRD ID		05470	17651
Ensembl ID		ENSG00000068028	ENSG00000122824
Uniprot IDs		Q9NS23	Q8NFP7
PDB IDs		2KZU	3MCF
Enriched GO Terms of Interacting Partners?
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