NUDT3 and DBN1

Data Source:
BioGRID (two hybrid)

		NUDT3	DBN1
Description		nudix hydrolase 3	drebrin 1
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GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol	Cytoplasm Cytoskeleton Actin Filament Plasma Membrane Gap Junction Postsynaptic Density Actin Cytoskeleton Lamellipodium Dendrite Growth Cone Site Of Polarized Growth Cortical Cytoskeleton Cortical Actin Cytoskeleton Actomyosin Postsynaptic Membrane Glutamatergic Synapse Postsynaptic Cytosol
	Molecular Function	Magnesium Ion Binding Endopolyphosphatase Activity Protein Binding Diphosphoinositol-polyphosphate Diphosphatase Activity Bis(5'-adenosyl)-hexaphosphatase Activity Bis(5'-adenosyl)-pentaphosphatase Activity M7G(5')pppN Diphosphatase Activity Inositol Diphosphate Tetrakisphosphate Diphosphatase Activity Inositol Diphosphate Pentakisphosphate Diphosphatase Activity	Actin Binding Protein Binding Profilin Binding Cadherin Binding Actin Filament Binding
	Biological Process	Cell-cell Signaling Diadenosine Polyphosphate Catabolic Process Inositol Phosphate Metabolic Process Diphosphoinositol Polyphosphate Metabolic Process Diphosphoinositol Polyphosphate Catabolic Process Diadenosine Pentaphosphate Catabolic Process Diadenosine Hexaphosphate Catabolic Process Adenosine 5'-(hexahydrogen Pentaphosphate) Catabolic Process	In Utero Embryonic Development Actin Filament Organization Cell Communication By Chemical Coupling Cell Communication By Electrical Coupling Regulation Of Actin Filament Polymerization Positive Regulation Of Synaptic Plasticity Maintenance Of Protein Location In Cell Positive Regulation Of Axon Extension Regulation Of Neuronal Synaptic Plasticity Neuron Projection Morphogenesis Regulation Of Dendrite Development Cytoplasmic Sequestering Of Protein Positive Regulation Of Dendritic Spine Morphogenesis Neural Precursor Cell Proliferation Postsynaptic Actin Cytoskeleton Organization Positive Regulation Of Receptor Localization To Synapse
Pathways		Synthesis of pyrophosphates in the cytosol
Drugs
Diseases
GWAS		Atrial fibrillation ( 29892015) Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Body mass index ( 29381148 20935630) Diastolic blood pressure ( 30224653) Estimated glomerular filtration rate ( 30604766) Height ( 25429064 19893584 31562340) Hip circumference ( 25673412) Myeloproliferative neoplasms ( 33057200) Refractive error ( 32231278)	Activated partial thromboplastin time ( 22703881) Extremely high intelligence ( 29520040) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (age <50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		36 interacting genes: ALAS1 APEX1 ARL6IP1 ASB13 CCL11 CHCHD3 DBN1 DDR1 DNAJA1 EEF1G FXYD3 HES1 ITFG1 MAF1 MCM5 MEX3B NR2C1 NUDT5 OAT PDCD5 PEX5 PRKD3 RAB17 REEP5 RNF126 RPL17 RPL8 RPLP1 SOX30 TNNT3 TUBA1A TUBGCP4 UBR1 VPS51 WDR74 XPNPEP1	27 interacting genes: ACD BAK1 BTRC CDK2AP2 DNMBP DUSP23 ESR1 FHL1 HOMER2 MAP1LC3B MAPK6 MEST NIPBL NUDT21 NUDT3 PFN1 POT1 PTEN RABGAP1L SNUPN SUPT5H TAB1 TERF1 TINF2 TPT1 UBE2D3 ZNF598
Entrez ID		11165	1627
HPRD ID		14849	00545
Ensembl ID		ENSG00000272325	ENSG00000113758
Uniprot IDs		O95989	Q16643
PDB IDs		2FVV 2Q9P 6PCK 6PCL	5Y1Z 5ZZ9
Enriched GO Terms of Interacting Partners?
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