NUDT3 and VPS51

Data Source:
BioGRID (two hybrid)

		NUDT3	VPS51
Description		nudix hydrolase 3	VPS51 subunit of GARP complex
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GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol	GARP Complex Nucleolus Golgi Apparatus Cytosol Membrane Integral Component Of Membrane Trans-Golgi Network Membrane Intracellular Membrane-bounded Organelle Recycling Endosome EARP Complex
	Molecular Function	Magnesium Ion Binding Endopolyphosphatase Activity Protein Binding Diphosphoinositol-polyphosphate Diphosphatase Activity Bis(5'-adenosyl)-hexaphosphatase Activity Bis(5'-adenosyl)-pentaphosphatase Activity M7G(5')pppN Diphosphatase Activity Inositol Diphosphate Tetrakisphosphate Diphosphatase Activity Inositol Diphosphate Pentakisphosphate Diphosphatase Activity	Molecular_function Protein Binding
	Biological Process	Cell-cell Signaling Diadenosine Polyphosphate Catabolic Process Inositol Phosphate Metabolic Process Diphosphoinositol Polyphosphate Metabolic Process Diphosphoinositol Polyphosphate Catabolic Process Diadenosine Pentaphosphate Catabolic Process Diadenosine Hexaphosphate Catabolic Process Adenosine 5'-(hexahydrogen Pentaphosphate) Catabolic Process	Lipid Transport Autophagy Golgi Organization Lysosomal Transport Protein Transport Endocytic Recycling Retrograde Transport, Endosome To Golgi Golgi Vesicle Transport Brain Morphogenesis
Pathways		Synthesis of pyrophosphates in the cytosol	Retrograde transport at the Trans-Golgi-Network
Drugs
Diseases
GWAS		Atrial fibrillation ( 29892015) Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Body mass index ( 29381148 20935630) Diastolic blood pressure ( 30224653) Estimated glomerular filtration rate ( 30604766) Height ( 25429064 19893584 31562340) Hip circumference ( 25673412) Myeloproliferative neoplasms ( 33057200) Refractive error ( 32231278)	Blood protein levels ( 28240269) Serum uric acid levels ( 32514006)
Interacting Genes		36 interacting genes: ALAS1 APEX1 ARL6IP1 ASB13 CCL11 CHCHD3 DBN1 DDR1 DNAJA1 EEF1G FXYD3 HES1 ITFG1 MAF1 MCM5 MEX3B NR2C1 NUDT5 OAT PDCD5 PEX5 PRKD3 RAB17 REEP5 RNF126 RPL17 RPL8 RPLP1 SOX30 TNNT3 TUBA1A TUBGCP4 UBR1 VPS51 WDR74 XPNPEP1	5 interacting genes: CDKN1A GSK3B NUDT3 VPS54 YTHDC1
Entrez ID		11165	738
HPRD ID		14849	12605
Ensembl ID		ENSG00000272325	ENSG00000149823
Uniprot IDs		O95989	Q9UID3
PDB IDs		2FVV 2Q9P 6PCK 6PCL	4J2C
Enriched GO Terms of Interacting Partners?
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