DBN1 and RABGAP1L

Data Source:
BioGRID (two hybrid)

		DBN1	RABGAP1L
Description		drebrin 1	RAB GTPase activating protein 1 like
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GO Annotations	Cellular Component	Cytoplasm Cytoskeleton Actin Filament Plasma Membrane Gap Junction Postsynaptic Density Actin Cytoskeleton Lamellipodium Dendrite Growth Cone Site Of Polarized Growth Cortical Cytoskeleton Cortical Actin Cytoskeleton Actomyosin Postsynaptic Membrane Glutamatergic Synapse Postsynaptic Cytosol	Nucleus Early Endosome Golgi Apparatus
	Molecular Function	Actin Binding Protein Binding Profilin Binding Cadherin Binding Actin Filament Binding	GTPase Activator Activity Small GTPase Binding
	Biological Process	In Utero Embryonic Development Actin Filament Organization Cell Communication By Chemical Coupling Cell Communication By Electrical Coupling Regulation Of Actin Filament Polymerization Positive Regulation Of Synaptic Plasticity Maintenance Of Protein Location In Cell Positive Regulation Of Axon Extension Regulation Of Neuronal Synaptic Plasticity Neuron Projection Morphogenesis Regulation Of Dendrite Development Cytoplasmic Sequestering Of Protein Positive Regulation Of Dendritic Spine Morphogenesis Neural Precursor Cell Proliferation Postsynaptic Actin Cytoskeleton Organization Positive Regulation Of Receptor Localization To Synapse	Intracellular Protein Transport Endocytosis Regulation Of Protein Localization Activation Of GTPase Activity
Pathways
Drugs
Diseases
GWAS		Activated partial thromboplastin time ( 22703881) Extremely high intelligence ( 29520040) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (age <50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)	Adult body size ( 32376654) Cerebrospinal fluid t-tau:AB1-42 ratio ( 26252872) Chronotype ( 30696823) Medication use (anilides) ( 31015401) Neutrophil count ( 32888494) Systemic lupus erythematosus ( 26606652 33536424) Tea consumption ( 31046077) White blood cell count ( 32888494)
Interacting Genes		27 interacting genes: ACD BAK1 BTRC CDK2AP2 DNMBP DUSP23 ESR1 FHL1 HOMER2 MAP1LC3B MAPK6 MEST NIPBL NUDT21 NUDT3 PFN1 POT1 PTEN RABGAP1L SNUPN SUPT5H TAB1 TERF1 TINF2 TPT1 UBE2D3 ZNF598	12 interacting genes: ACAP1 ARFGAP1 DBN1 GABARAPL1 MAP1LC3A RAB13 RAB34 RAB36 RB1 TSPAN2 UQCC2 WDFY3
Entrez ID		1627	9910
HPRD ID		00545	16464
Ensembl ID		ENSG00000113758	ENSG00000152061
Uniprot IDs		Q16643	B7ZAP0 F1LJ00 F5H8L0 Q5R372 Q9Y3L8
PDB IDs		5Y1Z 5ZZ9	3HZJ
Enriched GO Terms of Interacting Partners?
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