ADRM1 and RPN1

Data Source:
HPRD (in vitro)

		ADRM1	RPN1
Description		adhesion regulating molecule 1	ribophorin I
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GO Annotations	Cellular Component	Proteasome Complex Nucleoplasm Cytosol Plasma Membrane Proteasome Regulatory Particle, Lid Subcomplex	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Rough Endoplasmic Reticulum Cytosol Oligosaccharyltransferase Complex Membrane Integral Component Of Membrane Melanosome
	Molecular Function	Protease Binding Protein Binding Ubiquitin Binding Endopeptidase Activator Activity Proteasome Binding	RNA Binding Dolichyl-diphosphooligosaccharide-protein Glycotransferase Activity Protein Binding
	Biological Process	Transcription Elongation From RNA Polymerase II Promoter Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Endopeptidase Activity Protein Deubiquitination Proteasome Assembly	Cellular Protein Modification Process Protein N-linked Glycosylation Protein N-linked Glycosylation Via Asparagine
Pathways		UCH proteinases Ub-specific processing proteases	SRP-dependent cotranslational protein targeting to membrane Asparagine N-linked glycosylation Maturation of spike protein
Drugs
Diseases
GWAS		Prostate cancer ( 23535732)	Blood protein levels ( 30072576 29875488) Chronic obstructive pulmonary disease or high blood pressure (pleiotropy) ( 30940143) Eosinophil counts ( 29403010 27863252) Mean corpuscular hemoglobin ( 32888494) Mean corpuscular volume ( 32888494) Mild to moderate chronic kidney disease ( 31178898) Monocyte count ( 23314186 29403010 27863252) Monocyte percentage of white cells ( 32888494 27863252) Mosaic loss of chromosome Y (Y chromosome dosage) ( 31624269) Neutrophil count ( 32888494) Platelet distribution width ( 32888494) Sum eosinophil basophil counts ( 27863252) White blood cell count ( 32888494 21738480) White blood cell count (basophil) ( 29403010)
Interacting Genes		22 interacting genes: APP ATP6V0D2 CDC42 DDI1 EGFR MX1 PRKN PSMD1 PSMD14 PSMD2 PSMD4 RAD23A RAD23B RPN1 RPN2 SGTA SMURF1 UBC UBE3A UBQLN1 UBQLN2 UCHL5	17 interacting genes: ADRM1 CAMLG DPF1 DUX4 ERBB3 HSPA5 KRTAP1-3 RAD23A RBBP4 SGTA SIGIRR SMARCB1 UBC UBQLN1 UBQLN2 UBQLN4 WSB2
Entrez ID		11047	6184
HPRD ID		06440	01598
Ensembl ID		ENSG00000130706	ENSG00000163902
Uniprot IDs		A0A087WX59 Q16186	P04843
PDB IDs		2KQZ 2KR0 2L5V 2MKZ 2NBV 4UEL 4UEM 4WLQ 4WLR 5IRS 5V1Y 5V1Z 5YMY 6CO4 6OI4 6UYI 6UYJ	6S7O 6S7T
Enriched GO Terms of Interacting Partners?
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