ADRM1 and ATP6V0D2

Data Source:
BioGRID (two hybrid, affinity chromatography technology)

		ADRM1	ATP6V0D2
Description		adhesion regulating molecule 1	ATPase H+ transporting V0 subunit d2
Image			No pdb structure
GO Annotations	Cellular Component	Proteasome Complex Nucleoplasm Cytosol Plasma Membrane Proteasome Regulatory Particle, Lid Subcomplex	Lysosomal Membrane Early Endosome Endosome Membrane Membrane Apical Plasma Membrane Vacuolar Proton-transporting V-type ATPase Complex Phagocytic Vesicle Membrane Proton-transporting V-type ATPase, V0 Domain Plasma Membrane Proton-transporting V-type ATPase Complex Extracellular Exosome
	Molecular Function	Protease Binding Protein Binding Ubiquitin Binding Endopeptidase Activator Activity Proteasome Binding	Protein Binding Proton-transporting ATPase Activity, Rotational Mechanism
	Biological Process	Transcription Elongation From RNA Polymerase II Promoter Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Endopeptidase Activity Protein Deubiquitination Proteasome Assembly	Vacuolar Transport Vacuolar Acidification Insulin Receptor Signaling Pathway Regulation Of Macroautophagy Transferrin Transport Ion Transmembrane Transport Phagosome Acidification Proton Transmembrane Transport
Pathways		UCH proteinases Ub-specific processing proteases	ROS and RNS production in phagocytes Insulin receptor recycling Transferrin endocytosis and recycling Amino acids regulate mTORC1 Ion channel transport
Drugs			Tiludronic acid
Diseases
GWAS		Prostate cancer ( 23535732)	Adverse response to lamotrigine and phenytoin ( 22379998) Neutrophil count ( 32888494)
Interacting Genes		22 interacting genes: APP ATP6V0D2 CDC42 DDI1 EGFR MX1 PRKN PSMD1 PSMD14 PSMD2 PSMD4 RAD23A RAD23B RPN1 RPN2 SGTA SMURF1 UBC UBE3A UBQLN1 UBQLN2 UCHL5	20 interacting genes: ADRM1 AGO3 ARID5A CENPP CRX IKZF3 INCA1 MEOX2 NDUFB8 NICN1 PAX6 PHF12 POMC RBM15B REL RIBC1 RPS3 RUSC1 SEPTIN2 ZNF474
Entrez ID		11047	245972
HPRD ID		06440	16522
Ensembl ID		ENSG00000130706	ENSG00000147614
Uniprot IDs		A0A087WX59 Q16186	A0A024R991 Q8N8Y2
PDB IDs		2KQZ 2KR0 2L5V 2MKZ 2NBV 4UEL 4UEM 4WLQ 4WLR 5IRS 5V1Y 5V1Z 5YMY 6CO4 6OI4 6UYI 6UYJ
Enriched GO Terms of Interacting Partners?
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