ATP6V0D2 and SEPTIN2

Data Source:
BioGRID (two hybrid)

		ATP6V0D2	SEPTIN2
Description		ATPase H+ transporting V0 subunit d2	septin 2
Image		No pdb structure
GO Annotations	Cellular Component	Lysosomal Membrane Early Endosome Endosome Membrane Membrane Apical Plasma Membrane Vacuolar Proton-transporting V-type ATPase Complex Phagocytic Vesicle Membrane Proton-transporting V-type ATPase, V0 Domain Plasma Membrane Proton-transporting V-type ATPase Complex Extracellular Exosome	Exocyst Condensed Chromosome Kinetochore Nucleus Nucleoplasm Cytoplasm Spindle Plasma Membrane Axoneme Cell Cortex Septin Ring Synaptic Vesicle Actin Cytoskeleton Microtubule Cytoskeleton Midbody Septin Complex Cell Division Site Cleavage Furrow Photoreceptor Connecting Cilium Intercellular Bridge Perinuclear Region Of Cytoplasm Ciliary Membrane Extracellular Exosome Sperm Annulus Non-motile Cilium
	Molecular Function	Protein Binding Proton-transporting ATPase Activity, Rotational Mechanism	GTPase Activity Protein Binding GTP Binding Cadherin Binding Molecular Adaptor Activity
	Biological Process	Vacuolar Transport Vacuolar Acidification Insulin Receptor Signaling Pathway Regulation Of Macroautophagy Transferrin Transport Ion Transmembrane Transport Phagosome Acidification Proton Transmembrane Transport	Smoothened Signaling Pathway Spermatogenesis Regulation Of Exocytosis Neuron Projection Development Cellular Protein Localization Cilium Assembly Cytoskeleton-dependent Cytokinesis
Pathways		ROS and RNS production in phagocytes Insulin receptor recycling Transferrin endocytosis and recycling Amino acids regulate mTORC1 Ion channel transport	Anchoring of the basal body to the plasma membrane
Drugs		Tiludronic acid
Diseases
GWAS		Adverse response to lamotrigine and phenytoin ( 22379998) Neutrophil count ( 32888494)
Interacting Genes		20 interacting genes: ADRM1 AGO3 ARID5A CENPP CRX IKZF3 INCA1 MEOX2 NDUFB8 NICN1 PAX6 PHF12 POMC RBM15B REL RIBC1 RPS3 RUSC1 SEPTIN2 ZNF474	21 interacting genes: ATP6V0D2 BAZ2B CDC42 COG4 CSNK2A1 DAZAP2 ESR1 JPT2 MTOR PIK3R2 PLEKHF2 RNF31 S100A4 SEPTIN5 SEPTIN6 SEPTIN9 SH3KBP1 STMN1 STX1A TBC1D21 UBL5
Entrez ID		245972	4735
HPRD ID		16522	03297
Ensembl ID		ENSG00000147614	ENSG00000168385
Uniprot IDs		A0A024R991 Q8N8Y2	A0A384N6H6 Q15019
PDB IDs			2QA5 2QAG 2QNR 6UPA 6UPQ 6UPR
Enriched GO Terms of Interacting Partners?
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