RPP40 and POP7

Data Source:
HPRD (in vivo)

		RPP40	POP7
Description		ribonuclease P/MRP subunit p40	POP7 homolog, ribonuclease P/MRP subunit
Image
GO Annotations	Cellular Component	Ribonuclease MRP Complex Nucleus Nucleoplasm Nucleolar Ribonuclease P Complex Multimeric Ribonuclease P Complex	Ribonuclease MRP Complex Nucleus Nucleoplasm Nucleolus Cytoplasm Multimeric Ribonuclease P Complex Intracellular Membrane-bounded Organelle
	Molecular Function	Ribonuclease MRP Activity Ribonuclease P Activity Ribonuclease P RNA Binding	RNA Binding Ribonuclease P Activity Protein Binding Ribonuclease P RNA Binding
	Biological Process	Endonucleolytic Cleavage In ITS1 To Separate SSU-rRNA From 5.8S RRNA And LSU-rRNA From Tricistronic RRNA Transcript (SSU-rRNA, 5.8S RRNA, LSU-rRNA) TRNA 5'-leader Removal Endonucleolytic Cleavage Involved In TRNA Processing	TRNA 5'-leader Removal RRNA Processing TRNA Processing RNA Phosphodiester Bond Hydrolysis, Endonucleolytic
Pathways		tRNA processing in the nucleus Major pathway of rRNA processing in the nucleolus and cytosol	tRNA processing in the nucleus
Drugs
Diseases
GWAS			Hematocrit ( 32888494) Hemoglobin ( 32888494) Hemoglobin concentration ( 27863252) Low density lipoprotein cholesterol levels ( 32154731) Medication use (thyroid preparations) ( 31015401) Pursuit maintenance gain in psychotic disorders ( 29064472) Red blood cell count ( 32888494 27863252) Schizophrenia ( 30285260)
Interacting Genes		8 interacting genes: MEOX2 POP1 POP7 PTEN RPP14 RPP21 RPP30 RPP38	9 interacting genes: APP C9orf72 HSPB1 LAGE3 RPP25 RPP25L RPP38 RPP40 SMN1
Entrez ID		10799	10248
HPRD ID		09361	09357
Ensembl ID		ENSG00000124787	ENSG00000172336
Uniprot IDs		A0A087X1N3 O75818	O75817
PDB IDs		6AHR 6AHU 6AHV	6AHR 6AHU 6CWX
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?