CACNG3 and AP4M1

Data Source:
HPRD (two hybrid)

		CACNG3	AP4M1
Description		calcium voltage-gated channel auxiliary subunit gamma 3	adaptor related protein complex 4 subunit mu 1
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Voltage-gated Calcium Channel Complex Dendrite Endocytic Vesicle Membrane AMPA Glutamate Receptor Complex Somatodendritic Compartment Excitatory Synapse Schaffer Collateral - CA1 Synapse Postsynaptic Density Membrane Glutamatergic Synapse Integral Component Of Postsynaptic Density Membrane	Early Endosome Trans-Golgi Network Cytosol AP-4 Adaptor Complex Clathrin Adaptor Complex Cytoplasmic Vesicle Endosome Lumen Trans-Golgi Network Membrane Intracellular Membrane-bounded Organelle Extracellular Exosome
	Molecular Function	Voltage-gated Calcium Channel Activity Channel Regulator Activity PDZ Domain Binding Ionotropic Glutamate Receptor Binding	Protein Binding Protein Domain Specific Binding
	Biological Process	Protein Targeting Calcium Ion Transport Protein Localization Transmission Of Nerve Impulse Positive Regulation Of Synaptic Transmission, Glutamatergic Cardiac Conduction Calcium Ion Transmembrane Transport Neurotransmitter Receptor Transport, Postsynaptic Endosome To Lysosome Postsynaptic Neurotransmitter Receptor Diffusion Trapping Neurotransmitter Receptor Internalization Regulation Of AMPA Receptor Activity Positive Regulation Of AMPA Receptor Activity	Protein Targeting Protein Targeting To Lysosome Intracellular Protein Transport Golgi To Endosome Transport Protein Localization Vesicle-mediated Transport Golgi To Lysosome Transport Protein Localization To Basolateral Plasma Membrane
Pathways		Trafficking of AMPA receptors LGI-ADAM interactions	Lysosome Vesicle Biogenesis
Drugs		Ergocalciferol Enflurane Spironolactone Butamben Bioallethrin
Diseases			Cerebral palsy
GWAS		Chronotype ( 30696823) Metabolite levels ( 23823483)	Brain morphology (MOSTest) ( 32665545) Refractive error ( 32231278) Subcortical volume (MOSTest) ( 32665545)
Interacting Genes		2 interacting genes: AP4M1 APP	14 interacting genes: AP4B1 ARF1 CACNG3 CD63 CHTF8 DDX52 FNTA GRID2 GRIN2A GRIN2B LAMP2 TGOLN2 USP47 ZBTB22
Entrez ID		10368	9179
HPRD ID		05910	03803
Ensembl ID		ENSG00000006116	ENSG00000221838
Uniprot IDs		O60359	C9JC87 O00189
PDB IDs			3L81 4MDR
Enriched GO Terms of Interacting Partners?
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