AP4M1 and CHTF8

Data Source:
BioGRID (two hybrid)

		AP4M1	CHTF8
Description		adaptor related protein complex 4 subunit mu 1	chromosome transmission fidelity factor 8
Image			No pdb structure
GO Annotations	Cellular Component	Early Endosome Trans-Golgi Network Cytosol AP-4 Adaptor Complex Clathrin Adaptor Complex Cytoplasmic Vesicle Endosome Lumen Trans-Golgi Network Membrane Intracellular Membrane-bounded Organelle Extracellular Exosome	Nucleus Ctf18 RFC-like Complex
	Molecular Function	Protein Binding Protein Domain Specific Binding	DNA Clamp Loader Activity Single-stranded DNA Helicase Activity
	Biological Process	Protein Targeting Protein Targeting To Lysosome Intracellular Protein Transport Golgi To Endosome Transport Protein Localization Vesicle-mediated Transport Golgi To Lysosome Transport Protein Localization To Basolateral Plasma Membrane	DNA Replication Mitotic Sister Chromatid Cohesion DNA Duplex Unwinding Positive Regulation Of DNA-directed DNA Polymerase Activity
Pathways		Lysosome Vesicle Biogenesis	Polymerase switching on the C-strand of the telomere
Drugs
Diseases		Cerebral palsy
GWAS		Brain morphology (MOSTest) ( 32665545) Refractive error ( 32231278) Subcortical volume (MOSTest) ( 32665545)	Body mass index ( 26426971) Brain morphology (MOSTest) ( 32665545)
Interacting Genes		14 interacting genes: AP4B1 ARF1 CACNG3 CD63 CHTF8 DDX52 FNTA GRID2 GRIN2A GRIN2B LAMP2 TGOLN2 USP47 ZBTB22	6 interacting genes: AP4M1 DSCC1 EIF4EBP1 PCNA RFC3 WBP4
Entrez ID		9179	54921
HPRD ID		03803	16797
Ensembl ID		ENSG00000221838	ENSG00000168802
Uniprot IDs		C9JC87 O00189	P0CG13
PDB IDs		3L81 4MDR
Enriched GO Terms of Interacting Partners?
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