AP4M1 and DDX52

Data Source:
BioGRID (two hybrid)

		AP4M1	DDX52
Description		adaptor related protein complex 4 subunit mu 1	DExD-box helicase 52
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GO Annotations	Cellular Component	Early Endosome Trans-Golgi Network Cytosol AP-4 Adaptor Complex Clathrin Adaptor Complex Cytoplasmic Vesicle Endosome Lumen Trans-Golgi Network Membrane Intracellular Membrane-bounded Organelle Extracellular Exosome	Nucleoplasm Nucleolus Membrane
	Molecular Function	Protein Binding Protein Domain Specific Binding	RNA Binding RNA Helicase Activity ATP Binding
	Biological Process	Protein Targeting Protein Targeting To Lysosome Intracellular Protein Transport Golgi To Endosome Transport Protein Localization Vesicle-mediated Transport Golgi To Lysosome Transport Protein Localization To Basolateral Plasma Membrane	RRNA Processing Maturation Of SSU-rRNA
Pathways		Lysosome Vesicle Biogenesis	rRNA modification in the nucleus and cytosol Major pathway of rRNA processing in the nucleolus and cytosol
Drugs
Diseases		Cerebral palsy
GWAS		Brain morphology (MOSTest) ( 32665545) Refractive error ( 32231278) Subcortical volume (MOSTest) ( 32665545)	Ovarian cancer ( 23535730)
Interacting Genes		14 interacting genes: AP4B1 ARF1 CACNG3 CD63 CHTF8 DDX52 FNTA GRID2 GRIN2A GRIN2B LAMP2 TGOLN2 USP47 ZBTB22	5 interacting genes: AP4M1 HLCS MTNR1A PMP22 UTP23
Entrez ID		9179	11056
HPRD ID		03803	09911
Ensembl ID		ENSG00000221838	ENSG00000278053
Uniprot IDs		C9JC87 O00189	B3KM65 Q9Y2R4
PDB IDs		3L81 4MDR	3DKP
Enriched GO Terms of Interacting Partners?
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