RGS19 and GNAZ

Data Source:
HPRD (in vitro, two hybrid)

		RGS19	GNAZ
Description		regulator of G protein signaling 19	G protein subunit alpha z
Image			No pdb structure
GO Annotations	Cellular Component	Golgi Apparatus Plasma Membrane Brush Border Membrane Clathrin-coated Vesicle Membrane Raft	Nuclear Envelope Endoplasmic Reticulum Cytosol Heterotrimeric G-protein Complex Plasma Membrane
	Molecular Function	G-protein Alpha-subunit Binding GTPase Activity Protein Binding	G Protein-coupled Receptor Binding GTPase Activity Protein Binding GTP Binding G-protein Beta/gamma-subunit Complex Binding G Protein-coupled Serotonin Receptor Binding Metal Ion Binding
	Biological Process	Autophagy G Protein-coupled Receptor Signaling Pathway Small GTPase Mediated Signal Transduction Negative Regulation Of Signal Transduction Response To Ethanol	Protein Folding G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-modulating G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-inhibiting G Protein-coupled Receptor Signaling Pathway
Pathways		G alpha (q) signalling events G alpha (i) signalling events G alpha (i) signalling events G alpha (z) signalling events	PLC beta mediated events PLC beta mediated events G-protein activation G alpha (s) signalling events G alpha (i) signalling events G alpha (z) signalling events G alpha (z) signalling events Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding ADORA2B mediated anti-inflammatory cytokines production
Drugs
Diseases
GWAS		Cerebrospinal AB1-42 levels in normal cognition ( 29274321) Chronic kidney disease ( 31152163) Coronary artery disease ( 33020668) Estimated glomerular filtration rate ( 31152163) Mean corpuscular hemoglobin ( 32888494) Mean corpuscular volume ( 32888494 27863252) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Systolic blood pressure ( 30578418)	Handedness (Left-handed vs. non-left-handed) ( 31504236) Handedness (left-handed vs. right-handed) ( 31504236) Height ( 18391951) Processed meat consumption ( 32066663)
Interacting Genes		25 interacting genes: ALPP CATSPER1 CSNK2A1 CSNK2A2 GDE1 GIPC1 GNAI1 GNAI2 GNAI3 GNAO1 GNAZ HOXA1 KRTAP5-6 LCE4A MAPK1 MAPK6 NUFIP2 OPRL1 OSTM1 OTX1 POU4F2 PRKCA PSMA1 TGFBR1 VASN	16 interacting genes: ADORA1 APP DRD2 DRD5 EYA1 EYA2 LRRK1 NMT1 NUCB1 OPRD1 PRKCD RAP1GAP RGS10 RGS19 RGS20 RGS7
Entrez ID		10287	2781
HPRD ID		05461	00746
Ensembl ID		ENSG00000171700	ENSG00000128266
Uniprot IDs		B4DP94 P49795	P19086 Q8IY73
PDB IDs		1CMZ
Enriched GO Terms of Interacting Partners?
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