GNAZ and RGS10

Data Source:
HPRD (in vitro, in vivo)

		GNAZ	RGS10
Description		G protein subunit alpha z	regulator of G protein signaling 10
Image		No pdb structure
GO Annotations	Cellular Component	Nuclear Envelope Endoplasmic Reticulum Cytosol Heterotrimeric G-protein Complex Plasma Membrane	Nucleus Cytosol Plasma Membrane Neuronal Cell Body Dendritic Spine Axon Terminus
	Molecular Function	G Protein-coupled Receptor Binding GTPase Activity Protein Binding GTP Binding G-protein Beta/gamma-subunit Complex Binding G Protein-coupled Serotonin Receptor Binding Metal Ion Binding	G-protein Alpha-subunit Binding GTPase Activity GTPase Activator Activity Protein Binding
	Biological Process	Protein Folding G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-modulating G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-inhibiting G Protein-coupled Receptor Signaling Pathway	Response To Amphetamine G Protein-coupled Receptor Signaling Pathway G Protein-coupled Acetylcholine Receptor Signaling Pathway Regulation Of G Protein-coupled Receptor Signaling Pathway Negative Regulation Of Signal Transduction Positive Regulation Of GTPase Activity
Pathways		PLC beta mediated events PLC beta mediated events G-protein activation G alpha (s) signalling events G alpha (i) signalling events G alpha (z) signalling events G alpha (z) signalling events Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding ADORA2B mediated anti-inflammatory cytokines production	G alpha (i) signalling events G alpha (i) signalling events
Drugs
Diseases
GWAS		Handedness (Left-handed vs. non-left-handed) ( 31504236) Handedness (left-handed vs. right-handed) ( 31504236) Height ( 18391951) Processed meat consumption ( 32066663)	Depressive symptoms (stressful life events interaction) ( 27529621) Gut microbiota (bacterial taxa, rank normal transformation method) ( 32572223) Obstetric antiphospholipid syndrome ( 28424481)
Interacting Genes		16 interacting genes: ADORA1 APP DRD2 DRD5 EYA1 EYA2 LRRK1 NMT1 NUCB1 OPRD1 PRKCD RAP1GAP RGS10 RGS19 RGS20 RGS7	10 interacting genes: ADRB2 APP CALM1 GNAI1 GNAI3 GNAO1 GNAZ GNRHR PLEKHF2 PRKACA
Entrez ID		2781	6001
HPRD ID		00746	04172
Ensembl ID		ENSG00000128266	ENSG00000148908
Uniprot IDs		P19086 Q8IY73	O43665
PDB IDs			2DLR 2I59 2IHB
Enriched GO Terms of Interacting Partners?
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