BET1 and KCNJ6

Data Source:
BioGRID (two hybrid)

		BET1	KCNJ6
Description		Bet1 golgi vesicular membrane trafficking protein	potassium inwardly rectifying channel subfamily J member 6
Image			No pdb structure
GO Annotations	Cellular Component	Golgi Trans Cisterna Golgi Membrane Endoplasmic Reticulum Membrane Membrane Transport Vesicle Integral Component Of Golgi Membrane SNARE Complex Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane	Golgi Apparatus Plasma Membrane Voltage-gated Potassium Channel Complex
	Molecular Function	SNAP Receptor Activity Protein Binding	Inward Rectifier Potassium Channel Activity Protein Binding G-protein Activated Inward Rectifier Potassium Channel Activity
	Biological Process	Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Protein Transport COPII Vesicle Coating Vesicle Fusion With Golgi Apparatus	Potassium Ion Transport Regulation Of Ion Transmembrane Transport Potassium Ion Import Across Plasma Membrane
Pathways		COPII-mediated vesicle transport COPI-mediated anterograde transport	Activation of G protein gated Potassium channels Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
Drugs			Ethanol Halothane Ifenprodil Isavuconazole
Diseases
GWAS		Aging ( 22773346) Asparaginase hypersensitivity in acute lymphoblastic leukemia ( 25987655) BRCA1/2-negative high-risk breast cancer ( 30323354) Obesity-related traits ( 23251661) World class endurance athleticism ( 26824906)	Body size at age 10 ( 32376654) Electroencephalographic traits in alcoholism ( 22554406) Response to placebo treatment in childhood asthma (FVC change) ( 31557306) Rosacea symptom severity ( 29771307)
Interacting Genes		52 interacting genes: ADORA2A ANKS6 AQP6 ASGR2 ASZ1 BCL2L13 CD74 CD79A CGRRF1 CISD2 CLDN7 CLEC10A CRB3 CREB3L1 CYB561 CYBC1 ELOVL4 ERGIC3 FAM174A FAM209A FAM210B FAM9B GOSR2 GPR152 GPX8 JAGN1 KASH5 KCNJ6 LYPD5 MAGEA6 MFF MGST3 NAPB PTGES REEP4 RETREG3 SLC26A6 SLC7A14 SNTG2 SSMEM1 STX1A STX1B STX2 STX4 STX5 TMCO5A TMEM237 TMEM35A TMEM52B TMEM80 TMX2 USHBP1	63 interacting genes: ADRB2 AIG1 APOD BCL2L2 BET1 BIRC5 C14orf180 CMTM5 CNPY3 COL4A5 DLG1 DRD2 EDDM3B ERG28 FAM20B FIS1 FUNDC2 FXYD6 GABBR1 HMOX2 ICMT ITGAM KCNJ3 KCNJ9 LEPROTL1 LPAR3 LPCAT2 MIP MYO15B NINJ2 ORMDL2 PEX11G PEX16 PLLP PMP22 PNLIPRP1 RPRM RTP2 SCAMP4 SCARF1 SCD SERTM1 STATH STRIT1 SYT3 THSD7B TM6SF2 TMEM107 TMEM120B TMEM203 TMEM208 TMEM218 TMPPE TNFRSF10C TSPO2 UBIAD1 UNC50 UPK1B VSTM1 XIAP YIPF1 YIPF6 ZDHHC24
Entrez ID		10282	3763
HPRD ID		16107	02929
Ensembl ID		ENSG00000105829	ENSG00000157542
Uniprot IDs		O15155 Q53XK0	P48051
PDB IDs		3EGX
Enriched GO Terms of Interacting Partners?
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